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Page 1
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Rodina A, Xu C, Digwal CS, Joshi S, Patel Y, Santhaseela AR, Bay S, Merugu S, Alam A, Yan P, Yang C, Roychowdhury T, Panchal P, Shrestha L, Kang Y, Sharma S, Almodovar J, Corben A, Alpaugh ML, Modi S, Guzman ML, Fei T, Taldone T, Ginsberg SD, Erdjument-Bromage H, Neubert TA, Manova-Todorova K, Tsou MB, Young JC, Wang T, Chiosis G. Rodina A, et al. Nat Commun. 2023 Jun 23;14(1):3742. doi: 10.1038/s41467-023-39241-7. Nat Commun. 2023. PMID: 37353488 Free PMC article.
Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1).
Stephan G, Erdjument-Bromage H, Liu W, Frenster JD, Ravn-Boess N, Bready D, Cai J, Fenyo D, Neubert T, Placantonakis DG. Stephan G, et al. bioRxiv [Preprint]. 2023 Feb 9:2023.02.09.527921. doi: 10.1101/2023.02.09.527921. bioRxiv. 2023. Update in: Cell Rep. 2024 May 28;43(5):114229. doi: 10.1016/j.celrep.2024.114229 PMID: 36798364 Free PMC article. Updated. Preprint.
Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signaling.
Carbonell AU, Freire-Cobo C, Deyneko IV, Dobariya S, Erdjument-Bromage H, Clipperton-Allen AE, Page DT, Neubert TA, Jordan BA. Carbonell AU, et al. Front Aging Neurosci. 2023 May 15;15:1152562. doi: 10.3389/fnagi.2023.1152562. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37255534 Free PMC article.
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation.
McNutt SW, Roychowdhury T, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, DeStanchina E, Corben A, Modi S, Alpaugh M, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. McNutt SW, et al. Among authors: erdjument bromage h. Res Sq [Preprint]. 2024 Apr 3:rs.3.rs-4114038. doi: 10.21203/rs.3.rs-4114038/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Oct 16;15(1):8912. doi: 10.1038/s41467-024-53178-5 PMID: 38645031 Free PMC article. Updated. Preprint.
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1.
Stephan G, Haddock S, Wang S, Erdjument-Bromage H, Liu W, Ravn-Boess N, Frenster JD, Bready D, Cai J, Ronnen R, Sabio-Ortiz J, Fenyo D, Neubert TA, Placantonakis DG. Stephan G, et al. Among authors: erdjument bromage h. Cell Rep. 2024 May 28;43(5):114229. doi: 10.1016/j.celrep.2024.114229. Epub 2024 May 16. Cell Rep. 2024. PMID: 38758649 Free PMC article.
Structures of LRP2 reveal a molecular machine for endocytosis.
Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, Aziz Z, Robbins-Juarez SY, Chavez EY, Ahlsen G, Katsamba PS, Neubert TA, Fitzpatrick AWP, Barasch J, Shapiro L. Beenken A, et al. Cell. 2023 Feb 16;186(4):821-836.e13. doi: 10.1016/j.cell.2023.01.016. Epub 2023 Feb 6. Cell. 2023. PMID: 36750096 Free PMC article.
PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.
Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG. Frenster JD, et al. Among authors: erdjument bromage h. Cell Rep. 2023 Jul 25;42(7):112679. doi: 10.1016/j.celrep.2023.112679. Epub 2023 Jun 23. Cell Rep. 2023. PMID: 37354459 Free PMC article.
Spns1 is an iron transporter essential for megalin-dependent endocytosis.
Beenken A, Shen T, Jin G, Ghotra A, Xu K, Nesanir K, Sturley RE, Vijayakumar S, Khan A, Levitman A, Stauber J, Chavez EY, Robbins-Juarez SY, Hao L, Field TB, Erdjument-Bromage H, Neubert TA, Shapiro L, Qiu A, Barasch J. Beenken A, et al. Among authors: erdjument bromage h. Am J Physiol Renal Physiol. 2024 Nov 1;327(5):F775-F787. doi: 10.1152/ajprenal.00172.2024. Epub 2024 Sep 12. Am J Physiol Renal Physiol. 2024. PMID: 39265081 Free PMC article.
285 results