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Page 1
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Lei Y, VanPortfliet JJ, Chen YF, Bryant JD, Li Y, Fails D, Torres-Odio S, Ragan KB, Deng J, Mohan A, Wang B, Brahms ON, Yates SD, Spencer M, Tong CW, Bosenberg MW, West LC, Shadel GS, Shutt TE, Upton JW, Li P, West AP. Lei Y, et al. Among authors: ragan kb. Cell. 2023 Jul 6;186(14):3013-3032.e22. doi: 10.1016/j.cell.2023.05.039. Epub 2023 Jun 22. Cell. 2023. PMID: 37352855 Free PMC article.
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, Xu Y, Upton JW, Thomas PG, Green DR, Balachandran S. Zhang T, et al. Among authors: ragan kb. Cell. 2020 Mar 19;180(6):1115-1129.e13. doi: 10.1016/j.cell.2020.02.050. Cell. 2020. PMID: 32200799 Free PMC article.
Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.
Maelfait J, Liverpool L, Bridgeman A, Ragan KB, Upton JW, Rehwinkel J. Maelfait J, et al. Among authors: ragan kb. EMBO J. 2017 Sep 1;36(17):2529-2543. doi: 10.15252/embj.201796476. Epub 2017 Jul 17. EMBO J. 2017. PMID: 28716805 Free PMC article.
Host response: Neurons loosen the gRIP of death.
Ragan KB, Upton JW. Ragan KB, et al. Nat Microbiol. 2017 May 22;2:17090. doi: 10.1038/nmicrobiol.2017.90. Nat Microbiol. 2017. PMID: 28530667 No abstract available.
DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death.
Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, Upton JW, Balachandran S. Thapa RJ, et al. Among authors: ragan kb. Cell Host Microbe. 2016 Nov 9;20(5):674-681. doi: 10.1016/j.chom.2016.09.014. Epub 2016 Oct 13. Cell Host Microbe. 2016. PMID: 27746097 Free PMC article.