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Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression.
Kajitani N, Iwata M, Miura A, Tsunetomi K, Yamanashi T, Matsuo R, Nishiguchi T, Fukuda S, Nagata M, Shibushita M, Yamauchi T, Pu S, Shirayama Y, Watanabe K, Kaneko K. Kajitani N, et al. Among authors: yamanashi t. Neuropsychopharmacol Rep. 2020 Jun;40(2):157-165. doi: 10.1002/npr2.12099. Epub 2020 Mar 3. Neuropsychopharmacol Rep. 2020. PMID: 32125791 Free PMC article.
New Cutoff Scores for Delirium Screening Tools to Predict Patient Mortality.
Yamanashi T, Iwata M, Crutchley KJ, Sullivan EJ, Malicoat JR, Anderson ZM, Marra PS, Chang G, Kaneko K, Shinozaki E, Lee S, Shinozaki G. Yamanashi T, et al. J Am Geriatr Soc. 2021 Jan;69(1):140-147. doi: 10.1111/jgs.16815. Epub 2020 Sep 9. J Am Geriatr Soc. 2021. PMID: 32905636
Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model.
Yamanashi T, Iwata M, Shibushita M, Tsunetomi K, Nagata M, Kajitani N, Miura A, Matsuo R, Nishiguchi T, Kato TA, Setoyama D, Shirayama Y, Watanabe K, Shinozaki G, Kaneko K. Yamanashi T, et al. Sci Rep. 2020 Dec 10;10(1):21629. doi: 10.1038/s41598-020-78410-2. Sci Rep. 2020. PMID: 33303808 Free PMC article.
Bispectral EEG (BSEEG) quantifying neuro-inflammation in mice induced by systemic inflammation: A potential mouse model of delirium.
Yamanashi T, Malicoat JR, Steffen KT, Zarei K, Li R, Purnell BS, Najafi A, Saito K, Singh U, Toth BA, Lee S, Dailey ME, Cui H, Kaneko K, Cho HR, Iwata M, Buchanan GF, Shinozaki G. Yamanashi T, et al. J Psychiatr Res. 2021 Jan;133:205-211. doi: 10.1016/j.jpsychires.2020.12.036. Epub 2020 Dec 15. J Psychiatr Res. 2021. PMID: 33360427 Free article.
Stress increases blood beta-hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly in a rodent model.
Nishiguchi T, Iwata M, Kajitani N, Miura A, Matsuo R, Murakami S, Nakada Y, Pu S, Shimizu Y, Tsubakino T, Yamanashi T, Shinozaki G, Tsubota J, Shirayama Y, Watanabe K, Kaneko K. Nishiguchi T, et al. Among authors: yamanashi t. Neuropsychopharmacol Rep. 2021 Jun;41(2):159-167. doi: 10.1002/npr2.12164. Epub 2021 Feb 20. Neuropsychopharmacol Rep. 2021. PMID: 33609086 Free PMC article.
DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients.
Yamanashi T, Saito T, Yu T, Alario A, Comp K, Crutchley KJ, Sullivan EJ, Anderson ZM, Marra PS, Chang G, Wahba NE, Jellison SS, Meyer AA, Mathur S, Pandharipande P, Yoshino A, Kaneko K, Lee S, Toda H, Iwata M, Shinozaki G. Yamanashi T, et al. Neurobiol Aging. 2021 Sep;105:310-317. doi: 10.1016/j.neurobiolaging.2021.05.005. Epub 2021 May 21. Neurobiol Aging. 2021. PMID: 34192631
88 results