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886 results

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The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia.
Lechauve C, Keith J, Khandros E, Fowler S, Mayberry K, Freiwan A, Thom CS, Delbini P, Romero EB, Zhang J, Motta I, Tillman H, Cappellini MD, Kundu M, Weiss MJ. Lechauve C, et al. Among authors: keith j. Sci Transl Med. 2019 Aug 21;11(506):eaav4881. doi: 10.1126/scitranslmed.aav4881. Sci Transl Med. 2019. PMID: 31434755 Free PMC article.
Redox-Regulation of α-Globin in Vascular Physiology.
Kiger L, Keith J, Freiwan A, Fernandez AG, Tillman H, Isakson BE, Weiss MJ, Lechauve C. Kiger L, et al. Among authors: keith j. Antioxidants (Basel). 2022 Jan 14;11(1):159. doi: 10.3390/antiox11010159. Antioxidants (Basel). 2022. PMID: 35052663 Free PMC article.
Ancestral β-globin gene haplotypes modify β-thalassemia severity in a mouse model.
Lechauve C, Keith J, Dudley MW, Fernandez AG, Khandros E, Mayberry K, Mayuranathan T, Palmer L, Qiu X, Sheppard H, Telange R, Herz HM, Weiss MJ. Lechauve C, et al. Among authors: keith j. Blood Adv. 2024 Dec 10;8(23):5988-5992. doi: 10.1182/bloodadvances.2024012681. Blood Adv. 2024. PMID: 38536944 Free PMC article. No abstract available.
A glutamine metabolic switch supports erythropoiesis.
Lyu J, Gu Z, Zhang Y, Vu HS, Lechauve C, Cai F, Cao H, Keith J, Brancaleoni V, Granata F, Motta I, Cappellini MD, Huang LJ, DeBerardinis RJ, Weiss MJ, Ni M, Xu J. Lyu J, et al. Among authors: keith j. Science. 2024 Nov 15;386(6723):eadh9215. doi: 10.1126/science.adh9215. Epub 2024 Nov 15. Science. 2024. PMID: 39541460
The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study.
Negm L, Chung J, Nobre L, Bennett J, Fernandez NR, Nunes NM, Liu ZA, Komosa M, Aronson M, Zhang C, Stengs L, Bianchi V, Edwards M, Doherty S, Ercan AB, Cardenas MF, Macias M, Lueder MR, Ku M, Johnson M, Chang Y, Dimayacyac JR, Kraya AA, Guo Y, Naky S, Keith J, Gao AF, Munoz DG, Nguyen L, Tsang DS, Lim-Fat MJ, Das S, Shlien A, Ramaswamy V, Huang A, Malkin D, Villani A, Ertl-Wagner B, Levine A, Robinson GW, Pollock BH, Spector LG, Sei S, Dirks PB, Getz G, Nichols KE, Resnick AC, Wheeler DA, Das A, Maruvka YE, Hawkins C, Tabori U. Negm L, et al. Among authors: keith j. Lancet Oncol. 2024 Dec 16:S1470-2045(24)00640-5. doi: 10.1016/S1470-2045(24)00640-5. Online ahead of print. Lancet Oncol. 2024. PMID: 39701117
886 results