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Page 1
Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.
Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, Uhr M, Dose T, Unschuld PG, Zihl J, Binder E, Müller-Myhsok B, Holsboer F, Lucae S. Kloiber S, et al. Eur Neuropsychopharmacol. 2013 Jul;23(7):653-62. doi: 10.1016/j.euroneuro.2012.08.010. Epub 2012 Sep 29. Eur Neuropsychopharmacol. 2013. PMID: 23026132 Free PMC article.
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Latt… See abstract for full author list ➔ Köttgen A, et al. Among authors: kloiber s. Nat Genet. 2013 Feb;45(2):145-54. doi: 10.1038/ng.2500. Epub 2012 Dec 23. Nat Genet. 2013. PMID: 23263486 Free PMC article.
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
Czamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O'Donnell KJ, Garg E, Meaney MJ, Entringer S, Wadhwa PD, Buss C, Jones MJ, Lin DTS, MacIsaac JL, Kobor MS, Koen N, Zar HJ, Koenen KC, Dalvie S, Stein DJ, Kondofersky I, Müller NS, Theis FJ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Räikkönen K, Binder EB. Czamara D, et al. Nat Commun. 2019 Jun 11;10(1):2548. doi: 10.1038/s41467-019-10461-0. Nat Commun. 2019. PMID: 31186427 Free PMC article.
Characterization of the kindred of Alois Alzheimer's patient with plaque-only dementia.
Klünemann HH, Fronhöfer W, Werner-Füchtenbusch D, Grasbon-Frodl E, Kloiber S, Wurster HW, St George-Hyslop PH, Rogaeva E. Klünemann HH, et al. Among authors: kloiber s. Alzheimer Dis Assoc Disord. 2006 Oct-Dec;20(4):291-4. doi: 10.1097/01.wad.0000213855.81989.c8. Alzheimer Dis Assoc Disord. 2006. PMID: 17132975
Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine.
Gassen NC, Fries GR, Zannas AS, Hartmann J, Zschocke J, Hafner K, Carrillo-Roa T, Steinbacher J, Preißinger SN, Hoeijmakers L, Knop M, Weber F, Kloiber S, Lucae S, Chrousos GP, Carell T, Ising M, Binder EB, Schmidt MV, Rüegg J, Rein T. Gassen NC, et al. Among authors: kloiber s. Sci Signal. 2015 Nov 24;8(404):ra119. doi: 10.1126/scisignal.aac7695. Sci Signal. 2015. PMID: 26602018
Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders.
Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB. Unschuld PG, et al. Among authors: kloiber s. Am J Med Genet B Neuropsychiatr Genet. 2009 Dec 5;150B(8):1100-9. doi: 10.1002/ajmg.b.30938. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 19229853
155 results