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MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L, Reuben A, Heymach JV. Qian Y, et al. Among authors: deberardinis rj. Cancer Cell. 2023 Jul 10;41(7):1363-1380.e7. doi: 10.1016/j.ccell.2023.05.015. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327788 Free PMC article.
Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis.
Liu R, Ren X, Park YE, Feng H, Sheng X, Song X, AminiTabrizi R, Shah H, Li L, Zhang Y, Abdullah KG, Dubois-Coyne S, Lin H, Cole PA, DeBerardinis RJ, McBrayer SK, Huang H, Zhao Y. Liu R, et al. Among authors: deberardinis rj. Cell Metab. 2024 Dec 4:S1550-4131(24)00451-0. doi: 10.1016/j.cmet.2024.11.005. Online ahead of print. Cell Metab. 2024. PMID: 39642882
Novel pathogenic UQCRC2 variants in a female with normal neurodevelopment.
Abou Haidar L, Harris RC, Pachnis P, Chen H, Gotway GK, Ni M, DeBerardinis RJ. Abou Haidar L, et al. Among authors: deberardinis rj. Cold Spring Harb Mol Case Stud. 2024 Jan 10;9(4):a006295. doi: 10.1101/mcs.a006295. Print 2023 Dec. Cold Spring Harb Mol Case Stud. 2024. PMID: 37709555 Free PMC article.
290 results