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A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells.
Tan L, Duan X, Mutyala P, Zhou T, Amin S, Zhang T, Herbst B, Askan G, Itkin T, Xiang Z, Michelassi F, Lieberman MD, Iacobuzio-Donahue CA, Leach SD, Evans T, Chen S. Tan L, et al. Among authors: itkin t. J Mol Cell Biol. 2023 Nov 27;15(6):mjad039. doi: 10.1093/jmcb/mjad039. J Mol Cell Biol. 2023. PMID: 37327088 Free PMC article.
Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis.
Gomez-Salinero JM, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, Dufton N, Peghaire CR, Yokoyama M, Wingo M, Lu TM, Li G, Xiang JZ, Hsu YS, Redmond D, Schreiner R, Birdsey GM, Randi AM, Rafii S. Gomez-Salinero JM, et al. Among authors: itkin t. Nat Cardiovasc Res. 2022 Oct;1:882-899. doi: 10.1038/s44161-022-00128-3. Epub 2022 Oct 6. Nat Cardiovasc Res. 2022. PMID: 36713285 Free PMC article.
An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup.
Gower M, Li X, Aguilar-Navarro AG, Lin B, Fernandez M, Edun G, Nader M, Rondeau V, Arruda A, Tierens A, Eames Seffernick A, Pölönen P, Durocher J, Wagenblast E, Yang L, Lee HS, Mullighan CG, Teachey D, Rashkovan M, Tremblay CS, Herranz D, Itkin T, Loghavi S, Dick JE, Schwartz G, Perusini MA, Sibai H, Hitzler J, Gruber TA, Minden M, Jones CL, Dolgalev I, Jahangiri S, Tikhonova AN. Gower M, et al. Among authors: itkin t. Sci Transl Med. 2025 Jan;17(779):eadr2012. doi: 10.1126/scitranslmed.adr2012. Epub 2025 Jan 1. Sci Transl Med. 2025. PMID: 39742502
Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling.
Sarachakov A, Varlamova A, Svekolkin V, Polyakova M, Valencia I, Unkenholz C, Pannellini T, Galkin I, Ovcharov P, Tabakov D, Postovalova E, Shin N, Sethi I, Bagaev A, Itkin T, Crane G, Kluk M, Geyer J, Inghirami G, Patel S. Sarachakov A, et al. Among authors: itkin t. Blood. 2023 Dec 28;142(26):2282-2295. doi: 10.1182/blood.2023021280. Blood. 2023. PMID: 37774374 Free article.
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Spencer JA, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Itkin T, et al. bioRxiv [Preprint]. 2023 Mar 29:2023.03.27.534417. doi: 10.1101/2023.03.27.534417. bioRxiv. 2023. PMID: 37034724 Free PMC article. Preprint.
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.
Gómez-Salinero JM, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, Bram Y, Adelson RP, Lu TM, Inghirami G, Xiang JZ, Lis R, Redmond D, Schreiner R, Rabbany SY, Landau DA, Schwartz RE, Rafii S. Gómez-Salinero JM, et al. Among authors: itkin t. Cell Stem Cell. 2022 Apr 7;29(4):593-609.e7. doi: 10.1016/j.stem.2022.03.002. Epub 2022 Mar 31. Cell Stem Cell. 2022. PMID: 35364013 Free PMC article.
44 results