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Page 1
Mechanisms driving the ageing heart.
Anderson R, Richardson GD, Passos JF. Anderson R, et al. Among authors: passos jf. Exp Gerontol. 2018 Aug;109:5-15. doi: 10.1016/j.exger.2017.10.015. Epub 2017 Oct 18. Exp Gerontol. 2018. PMID: 29054534 Review.
Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice.
Correia-Melo C, Birch J, Fielder E, Rahmatika D, Taylor J, Chapman J, Lagnado A, Carroll BM, Miwa S, Richardson G, Jurk D, Oakley F, Mann J, Mann DA, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: passos jf. Aging Cell. 2019 Feb;18(1):e12882. doi: 10.1111/acel.12882. Epub 2018 Nov 23. Aging Cell. 2019. PMID: 30468013 Free PMC article.
Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens A, Greaves LC, Kolsky KL, Parini A, Douin-Echinard V, LeBrasseur NK, Arthur HM, Tual-Chalot S, Schafer MJ, Roos CM, Miller JD, Robertson N, Mann J, Adams PD, Tchkonia T, Kirkland JL, Mialet-Perez J, Richardson GD, Passos JF. Anderson R, et al. Among authors: passos jf. EMBO J. 2019 Mar 1;38(5):e100492. doi: 10.15252/embj.2018100492. Epub 2019 Feb 8. EMBO J. 2019. PMID: 30737259 Free PMC article.
Therapeutic Potential of Senolytics in Cardiovascular Disease.
Dookun E, Passos JF, Arthur HM, Richardson GD. Dookun E, et al. Among authors: passos jf. Cardiovasc Drugs Ther. 2022 Feb;36(1):187-196. doi: 10.1007/s10557-020-07075-w. Epub 2020 Sep 26. Cardiovasc Drugs Ther. 2022. PMID: 32979174 Free PMC article. Review.
Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery.
Dookun E, Walaszczyk A, Redgrave R, Palmowski P, Tual-Chalot S, Suwana A, Chapman J, Jirkovsky E, Donastorg Sosa L, Gill E, Yausep OE, Santin Y, Mialet-Perez J, Andrew Owens W, Grieve D, Spyridopoulos I, Taggart M, Arthur HM, Passos JF, Richardson GD. Dookun E, et al. Among authors: passos jf. Aging Cell. 2020 Oct;19(10):e13249. doi: 10.1111/acel.13249. Epub 2020 Sep 29. Aging Cell. 2020. PMID: 32996233 Free PMC article.
Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.
Ogrodnik M, Evans SA, Fielder E, Victorelli S, Kruger P, Salmonowicz H, Weigand BM, Patel AD, Pirtskhalava T, Inman CL, Johnson KO, Dickinson SL, Rocha A, Schafer MJ, Zhu Y, Allison DB, von Zglinicki T, LeBrasseur NK, Tchkonia T, Neretti N, Passos JF, Kirkland JL, Jurk D. Ogrodnik M, et al. Among authors: passos jf. Aging Cell. 2021 Feb;20(2):e13296. doi: 10.1111/acel.13296. Epub 2021 Jan 20. Aging Cell. 2021. PMID: 33470505 Free PMC article.
128 results