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Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function.
Pietsch N, Chen CY, Kupsch S, Bacmeister L, Geertz B, Herera-Rivero M, Voß H, Krämer E, Braren I, Westermann D, Schlüter H, Mearini G, Schlossarek S, van der Velden J, Caporizzo MA, Lindner D, Prosser BL, Carrier L. Pietsch N, et al. Among authors: schlossarek s. bioRxiv [Preprint]. 2024 Feb 7:2023.05.25.542365. doi: 10.1101/2023.05.25.542365. bioRxiv. 2024. Update in: Circ Res. 2024 Oct 11;135(9):910-932. doi: 10.1161/CIRCRESAHA.124.324387 PMID: 37292763 Free PMC article. Updated. Preprint.
The ubiquitin-proteasome system in cardiac dysfunction.
Mearini G, Schlossarek S, Willis MS, Carrier L. Mearini G, et al. Among authors: schlossarek s. Biochim Biophys Acta. 2008 Dec;1782(12):749-63. doi: 10.1016/j.bbadis.2008.06.009. Epub 2008 Jun 25. Biochim Biophys Acta. 2008. PMID: 18634872 Free article. Review.
Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Vignier N, Schlossarek S, Fraysse B, Mearini G, Krämer E, Pointu H, Mougenot N, Guiard J, Reimer R, Hohenberg H, Schwartz K, Vernet M, Eschenhagen T, Carrier L. Vignier N, et al. Among authors: schlossarek s. Circ Res. 2009 Jul 31;105(3):239-48. doi: 10.1161/CIRCRESAHA.109.201251. Epub 2009 Jul 9. Circ Res. 2009. PMID: 19590044
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L. Mearini G, et al. Among authors: schlossarek s. Cardiovasc Res. 2010 Jan 15;85(2):357-66. doi: 10.1093/cvr/cvp348. Epub 2009 Oct 22. Cardiovasc Res. 2010. PMID: 19850579 Free PMC article.
Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice.
Gedicke-Hornung C, Behrens-Gawlik V, Reischmann S, Geertz B, Stimpel D, Weinberger F, Schlossarek S, Précigout G, Braren I, Eschenhagen T, Mearini G, Lorain S, Voit T, Dreyfus PA, Garcia L, Carrier L. Gedicke-Hornung C, et al. Among authors: schlossarek s. EMBO Mol Med. 2013 Jul;5(7):1128-45. doi: 10.1002/emmm.201202168. Epub 2013 May 29. EMBO Mol Med. 2013. PMID: 23716398 Free PMC article.
52 results