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Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function.
Pietsch N, Chen CY, Kupsch S, Bacmeister L, Geertz B, Herera-Rivero M, Voß H, Krämer E, Braren I, Westermann D, Schlüter H, Mearini G, Schlossarek S, van der Velden J, Caporizzo MA, Lindner D, Prosser BL, Carrier L. Pietsch N, et al. Among authors: carrier l. bioRxiv [Preprint]. 2024 Feb 7:2023.05.25.542365. doi: 10.1101/2023.05.25.542365. bioRxiv. 2024. Update in: Circ Res. 2024 Oct 11;135(9):910-932. doi: 10.1161/CIRCRESAHA.124.324387 PMID: 37292763 Free PMC article. Updated. Preprint.
The ubiquitin-proteasome system in cardiac dysfunction.
Mearini G, Schlossarek S, Willis MS, Carrier L. Mearini G, et al. Among authors: carrier l. Biochim Biophys Acta. 2008 Dec;1782(12):749-63. doi: 10.1016/j.bbadis.2008.06.009. Epub 2008 Jun 25. Biochim Biophys Acta. 2008. PMID: 18634872 Free article. Review.
Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Vignier N, Schlossarek S, Fraysse B, Mearini G, Krämer E, Pointu H, Mougenot N, Guiard J, Reimer R, Hohenberg H, Schwartz K, Vernet M, Eschenhagen T, Carrier L. Vignier N, et al. Among authors: carrier l. Circ Res. 2009 Jul 31;105(3):239-48. doi: 10.1161/CIRCRESAHA.109.201251. Epub 2009 Jul 9. Circ Res. 2009. PMID: 19590044
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
Mearini G, Gedicke C, Schlossarek S, Witt CC, Krämer E, Cao P, Gomes MD, Lecker SH, Labeit S, Willis MS, Eschenhagen T, Carrier L. Mearini G, et al. Among authors: carrier l. Cardiovasc Res. 2010 Jan 15;85(2):357-66. doi: 10.1093/cvr/cvp348. Epub 2009 Oct 22. Cardiovasc Res. 2010. PMID: 19850579 Free PMC article.
The ubiquitin-proteasome system in cardiomyopathies.
Schlossarek S, Carrier L. Schlossarek S, et al. Among authors: carrier l. Curr Opin Cardiol. 2011 May;26(3):190-5. doi: 10.1097/HCO.0b013e32834598fe. Curr Opin Cardiol. 2011. PMID: 21415726 Review.
Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice.
Fraysse B, Weinberger F, Bardswell SC, Cuello F, Vignier N, Geertz B, Starbatty J, Krämer E, Coirault C, Eschenhagen T, Kentish JC, Avkiran M, Carrier L. Fraysse B, et al. Among authors: carrier l. J Mol Cell Cardiol. 2012 Jun;52(6):1299-307. doi: 10.1016/j.yjmcc.2012.03.009. Epub 2012 Mar 23. J Mol Cell Cardiol. 2012. PMID: 22465693 Free PMC article.
261 results