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Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials.
Haney M, Vallée M, Fabre S, Collins Reed S, Zanese M, Campistron G, Arout CA, Foltin RW, Cooper ZD, Kearney-Ramos T, Metna M, Justinova Z, Schindler C, Hebert-Chatelain E, Bellocchio L, Cathala A, Bari A, Serrat R, Finlay DB, Caraci F, Redon B, Martín-García E, Busquets-Garcia A, Matias I, Levin FR, Felpin FX, Simon N, Cota D, Spampinato U, Maldonado R, Shaham Y, Glass M, Thomsen LL, Mengel H, Marsicano G, Monlezun S, Revest JM, Piazza PV. Haney M, et al. Among authors: shaham y. Nat Med. 2023 Jun;29(6):1487-1499. doi: 10.1038/s41591-023-02381-w. Epub 2023 Jun 8. Nat Med. 2023. PMID: 37291212 Free PMC article. Clinical Trial.
The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys.
Justinova Z, Panlilio LV, Secci ME, Redhi GH, Schindler CW, Cross AJ, Mrzljak L, Medd A, Shaham Y, Goldberg SR. Justinova Z, et al. Among authors: shaham y. Biol Psychiatry. 2015 Oct 1;78(7):452-62. doi: 10.1016/j.biopsych.2015.01.014. Epub 2015 Feb 7. Biol Psychiatry. 2015. PMID: 25802079 Free PMC article.
Orbitofrontal activation restores insight lost after cocaine use.
Lucantonio F, Takahashi YK, Hoffman AF, Chang CY, Bali-Chaudhary S, Shaham Y, Lupica CR, Schoenbaum G. Lucantonio F, et al. Among authors: shaham y. Nat Neurosci. 2014 Aug;17(8):1092-9. doi: 10.1038/nn.3763. Epub 2014 Jul 20. Nat Neurosci. 2014. PMID: 25042581 Free PMC article.
Silent synapses dictate cocaine memory destabilization and reconsolidation.
Wright WJ, Graziane NM, Neumann PA, Hamilton PJ, Cates HM, Fuerst L, Spenceley A, MacKinnon-Booth N, Iyer K, Huang YH, Shaham Y, Schlüter OM, Nestler EJ, Dong Y. Wright WJ, et al. Among authors: shaham y. Nat Neurosci. 2020 Jan;23(1):32-46. doi: 10.1038/s41593-019-0537-6. Epub 2019 Dec 2. Nat Neurosci. 2020. PMID: 31792465 Free PMC article.
268 results