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Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.
Obermann W, Azri MFD, Konopka L, Schmidt N, Magari F, Sherman J, Silva LMR, Hermosilla C, Ludewig AH, Houhou H, Haeberlein S, Luo MY, Häcker I, Schetelig MF, Grevelding CG, Schroeder FC, Lau GSK, Taubert A, Rodriguez A, Heine A, Yeo TC, Grünweller A, Taroncher-Oldenburg G. Obermann W, et al. Among authors: houhou h. Sci Rep. 2023 Jun 8;13(1):9297. doi: 10.1038/s41598-023-35765-6. Sci Rep. 2023. PMID: 37291191 Free PMC article.
Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram.
Beutler M, Harnischfeger J, Weber MHW, Hahnel SR, Quack T, Blohm A, Ueberall ME, Timm T, Lochnit G, Rennar GA, Gallinger TL, Houhou H, Rahlfs S, Falcone FH, Becker K, Schlitzer M, Haeberlein S, Czermak P, Salzig D, Grevelding CG. Beutler M, et al. Among authors: houhou h. Eur J Med Chem. 2023 May 5;251:115179. doi: 10.1016/j.ejmech.2023.115179. Epub 2023 Feb 10. Eur J Med Chem. 2023. PMID: 36948075 Free article.