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A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, McKeigue PM, Valo E, Forsblom C, Harjutsalo V; Finnish Diabetic Nephropathy Study (FinnDiane); Perna A, Rurali E, Marcovecchio ML, Igo RP Jr, Salem RM, Perico N, Lajer M, Käräjämäki A, Imamura M, Kubo M, Takahashi A, Sim X, Liu J, van Dam RM, Jiang G, Tam CHT, Luk AOY, Lee HM, Lim CKP, Szeto CC, So WY, Chan JCN; Hong Kong Diabetes Registry Theme-based Research Scheme Project Group; Ang SF, Dorajoo R, Wang L, Clara TSH, McKnight AJ, Duffy S; Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group; Pezzolesi MG; GENIE (GEnetics of Nephropathy an International Effort) Consortium; Marre M, Gyorgy B, Hadjadj S, Hiraki LT; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group; Ahluwalia TS, Almgren P, Schulz CA, Orho-Melander M, Linneberg A, Christensen C, Witte DR, Grarup N, Brandslund I, Melander O, Paterson AD, Tregouet D, Maxwell AP, Lim SC, Ma RCW, Tai ES, Maeda S, Lyssenko V, Tuomi T, Krolewski AS, Rich SS, Hirschhorn JN, Florez JC, Dunger D, Pedersen O, Hansen T, Rossing P, Remuzz… See abstract for full author list ➔ van Zuydam NR, et al. Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27. Diabetes. 2018. PMID: 29703844 Free PMC article.
OSA Is Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study.
Baldanzi G, Sayols-Baixeras S, Theorell-Haglöw J, Dekkers KF, Hammar U, Nguyen D, Lin YT, Ahmad S, Holm JB, Nielsen HB, Brunkwall L, Benedict C, Cedernaes J, Koskiniemi S, Phillipson M, Lind L, Sundström J, Bergström G, Engström G, Smith JG, Orho-Melander M, Ärnlöv J, Kennedy B, Lindberg E, Fall T. Baldanzi G, et al. Chest. 2023 Aug;164(2):503-516. doi: 10.1016/j.chest.2023.03.010. Epub 2023 Mar 15. Chest. 2023. PMID: 36925044 Free PMC article.
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Luukkonen PK, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669104 Free PMC article.
Accelerometer-based physical activity is associated with the gut microbiota in 8416 individuals in SCAPIS.
Baldanzi G, Sayols-Baixeras S, Ekblom-Bak E, Ekblom Ö, Dekkers KF, Hammar U, Nguyen D, Ahmad S, Ericson U, Arvidsson D, Börjesson M, Johanson PJ, Smith JG, Bergström G, Lind L, Engström G, Ärnlöv J, Kennedy B, Orho-Melander M, Fall T. Baldanzi G, et al. EBioMedicine. 2024 Feb;100:104989. doi: 10.1016/j.ebiom.2024.104989. Epub 2024 Jan 31. EBioMedicine. 2024. PMID: 38301483 Free PMC article.
A Swedish dietary guideline index, gut microbial α-diversity and prevalence of metabolic syndrome - observations in the Swedish CArdioPulmonary bioImage Study (SCAPIS).
Ericson U, Hellstrand S, Larsson A, Miari M, Sayols-Baixeras S, Dekkers KF, Bergström G, Malinovschi A, Engström G, Ärnlöv J, Fall T, Orho-Melander M. Ericson U, et al. Among authors: orho melander m. Food Nutr Res. 2024 Nov 28;68. doi: 10.29219/fnr.v68.10547. eCollection 2024. Food Nutr Res. 2024. PMID: 39691688 Free PMC article.
Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis.
Singh P, Sun J, Cavalera M, Al-Sharify D, Matthes F, Barghouth M, Tengryd C, Dunér P, Persson A, Sundius L, Nitulescu M, Bengtsson E, Rattik S, Engelbertsen D, Orho-Melander M, Nilsson J, Monaco C, Goncalves I, Edsfeldt A. Singh P, et al. Among authors: orho melander m. Nat Commun. 2024 Dec 9;15(1):10464. doi: 10.1038/s41467-024-50753-8. Nat Commun. 2024. PMID: 39653743 Free PMC article.
New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population.
Larsson A, Ericson U, Jönsson D, Miari M, Athanasiadis P, Baldanzi G, Brunkwall L, Hellstrand S, Klinge B, Melander O, Nilsson PM, Fall T, Maziarz M, Orho-Melander M. Larsson A, et al. Among authors: orho melander m. Sci Rep. 2024 Oct 10;14(1):23723. doi: 10.1038/s41598-024-71571-4. Sci Rep. 2024. PMID: 39390025 Free PMC article.
341 results