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Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture.
Sun J, Singh P, Shami A, Kluza E, Pan M, Djordjevic D, Michaelsen NB, Kennbäck C, van der Wel NN, Orho-Melander M, Nilsson J, Formentini I, Conde-Knape K, Lutgens E, Edsfeldt A, Gonçalves I. Sun J, et al. Among authors: lutgens e. J Am Coll Cardiol. 2023 Jun 13;81(23):2213-2227. doi: 10.1016/j.jacc.2023.04.008. J Am Coll Cardiol. 2023. PMID: 37286250 Free article.
Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis increasing the risk of cerebrovascular complications.
Dib L, Koneva LA, Edsfeldt A, Zurke YX, Sun J, Nitulescu M, Attar M, Lutgens E, Schmidt S, Lindholm MW, Choudhury RP, Cassimjee I, Lee R, Handa A, Goncalves I, Sansom SN, Monaco C. Dib L, et al. Among authors: lutgens e. Nat Cardiovasc Res. 2023 Jun 26;2(7):656-672. doi: 10.1038/s44161-023-00295-x. Nat Cardiovasc Res. 2023. PMID: 38362263 Free PMC article.
Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification.
Pavlic A, Poelman H, Wasilewski G, Wichapong K, Lux P, Maassen C, Lutgens E, Schurgers LJ, Reutelingsperger CP, Nicolaes GAF. Pavlic A, et al. Among authors: lutgens e. Int J Mol Sci. 2023 Jan 19;24(3):2027. doi: 10.3390/ijms24032027. Int J Mol Sci. 2023. PMID: 36768348 Free PMC article.
Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice.
In Het Panhuis W, Schönke M, Modder M, Tom HE, Lalai RA, Pronk ACM, Streefland TCM, van Kerkhof LWM, Dollé MET, Depuydt MAC, Bot I, Vos WG, Bosmans LA, van Os BW, Lutgens E, Rensen PCN, Kooijman S. In Het Panhuis W, et al. Among authors: lutgens e. EBioMedicine. 2023 Jul;93:104680. doi: 10.1016/j.ebiom.2023.104680. Epub 2023 Jun 23. EBioMedicine. 2023. PMID: 37356205 Free PMC article.
Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1-/-Ldlr-/- mice.
Porteiro B, Roscam Abbing RLP, In Het Panhuis W, de Waart DR, Duijst S, Bolt I, Vogels EW, Levels JHM, Bosmans LA, Vos WG, Oude Elferink RPJ, Lutgens E, van de Graaf SFJ. Porteiro B, et al. Among authors: lutgens e. J Lipid Res. 2024 Aug;65(8):100594. doi: 10.1016/j.jlr.2024.100594. Epub 2024 Jul 14. J Lipid Res. 2024. PMID: 39009243 Free PMC article.
The IRAK-M death domain: a tale of three surfaces.
Gürkan B, Poelman H, Pereverzeva L, Kruijswijk D, de Vos AF, Groenen AG, Nollet EE, Wichapong K, Lutgens E, van der Poll T, Du J, Wiersinga WJ, Nicolaes GAF, van 't Veer C. Gürkan B, et al. Among authors: lutgens e. Front Mol Biosci. 2024 Jan 10;10:1265455. doi: 10.3389/fmolb.2023.1265455. eCollection 2023. Front Mol Biosci. 2024. PMID: 38268724 Free PMC article.
Unrestrained cancer immunity ignites atherosclerosis.
Williams JW, Lutgens E. Williams JW, et al. Among authors: lutgens e. Nat Cardiovasc Res. 2024 Dec;3(12):1380-1382. doi: 10.1038/s44161-024-00571-4. Nat Cardiovasc Res. 2024. PMID: 39613874 No abstract available.
246 results