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Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.
Kiss MG, Papac-Miličević N, Porsch F, Tsiantoulas D, Hendrikx T, Takaoka M, Dinh HQ, Narzt MS, Göderle L, Ozsvár-Kozma M, Schuster M, Fortelny N, Hladik A, Knapp S, Gruber F, Pickering MC, Bock C, Swirski FK, Ley K, Zernecke A, Cochain C, Kemper C, Mallat Z, Binder CJ. Kiss MG, et al. Among authors: binder cj. Immunity. 2023 Aug 8;56(8):1809-1824.e10. doi: 10.1016/j.immuni.2023.06.026. Epub 2023 Jul 26. Immunity. 2023. PMID: 37499656 Free PMC article.
Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity.
Dennis E, Murach M, Blackburn CMR, Marshall M, Root K, Pattarabanjird T, Deroissart J, Erickson LD, Binder CJ, Bekiranov S, McNamara CA. Dennis E, et al. Among authors: binder cj. Front Immunol. 2024 Mar 27;15:1380641. doi: 10.3389/fimmu.2024.1380641. eCollection 2024. Front Immunol. 2024. PMID: 38601144 Free PMC article.
Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis.
van Os BW, Kusters PJH, den Toom M, Beckers L, van Tiel CM, Vos WG, de Jong E, Kieser A, van Roomen C, Binder CJ, Reiche ME, de Winther MP, Bosmans LA, Lutgens E. van Os BW, et al. Among authors: binder cj. Front Cardiovasc Med. 2023 May 5;10:1171764. doi: 10.3389/fcvm.2023.1171764. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37215541 Free PMC article.
TREM2 protects from atherosclerosis by limiting necrotic core formation.
Piollet M, Porsch F, Rizzo G, Kapser F, Schulz DJJ, Kiss MG, Schlepckow K, Morenas-Rodriguez E, Sen MO, Gropper J, Bandi SR, Schäfer S, Krammer T, Leipold AM, Hoke M, Ozsvár-Kozma M, Beneš H, Schillinger M, Minar E, Roesch M, Göderle L, Hladik A, Knapp S, Colonna M, Martini R, Saliba AE, Haass C, Zernecke A, Binder CJ, Cochain C. Piollet M, et al. Among authors: binder cj. Nat Cardiovasc Res. 2024 Mar;3(3):269-282. doi: 10.1038/s44161-024-00429-9. Epub 2024 Mar 12. Nat Cardiovasc Res. 2024. PMID: 38974464 Free PMC article.
Apolipoprotein B-containing lipoproteins in atherogenesis.
Borén J, Packard CJ, Binder CJ. Borén J, et al. Among authors: binder cj. Nat Rev Cardiol. 2025 Jan 2. doi: 10.1038/s41569-024-01111-0. Online ahead of print. Nat Rev Cardiol. 2025. PMID: 39743565 Review.
Lower your cholesterol early, and stick with it!
Swirski FK, Binder CJ. Swirski FK, et al. Among authors: binder cj. Nat Rev Cardiol. 2024 Oct 18. doi: 10.1038/s41569-024-01095-x. Online ahead of print. Nat Rev Cardiol. 2024. PMID: 39424909 No abstract available.
224 results