Pyta K - Search Results

1

Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity.

Skrzypczak N, Pyta K, Bohusz W, Leśniewska A, Gdaniec M, Ruszkowski P, Schilf W, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: pyta k. J Org Chem. 2023 Jul 7;88(13):9469-9474. doi: 10.1021/acs.joc.3c00493. Epub 2023 Jun 5. J Org Chem. 2023. PMID: 37276434 Free PMC article.

2

The influence of protonation on molecular structure and physico-chemical properties of gossypol Schiff bases.

Przybylski P, Pyta K, Czupryniak J, Wicher B, Gdaniec M, Ossowski T, Brzezinski B. Przybylski P, et al. Among authors: pyta k. Org Biomol Chem. 2010 Dec 21;8(24):5511-8. doi: 10.1039/c0ob00288g. Epub 2010 Oct 19. Org Biomol Chem. 2010. PMID: 20959900

3

Intramolecular proton transfer impact on antibacterial properties of ansamycin antibiotic rifampicin and its new amino analogues.

Pyta K, Przybylski P, Wicher B, Gdaniec M, Stefańska J. Pyta K, et al. Org Biomol Chem. 2012 Mar 28;10(12):2385-8. doi: 10.1039/c2ob00008c. Epub 2012 Feb 20. Org Biomol Chem. 2012. PMID: 22349158

4

A new model of binding of rifampicin and its amino analogues as zwitterions to bacterial RNA polymerase.

Pyta K, Przybylski P, Klich K, Stefańska J. Pyta K, et al. Org Biomol Chem. 2012 Oct 3;10(41):8283-97. doi: 10.1039/c2ob26317c. Org Biomol Chem. 2012. PMID: 22964663

5

Regio- and Stereoselective Functionalization of 16-Membered Lactone Aglycone of Spiramycin via Cascade Strategy.

Klich K, Pyta K, Przybylski P. Klich K, et al. Among authors: pyta k. J Org Chem. 2015 Jul 17;80(14):7040-9. doi: 10.1021/acs.joc.5b00847. Epub 2015 Jul 1. J Org Chem. 2015. PMID: 26083900

6

Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm.

Klich K, Pyta K, Kubicka MM, Ruszkowski P, Celewicz L, Gajecka M, Przybylski P. Klich K, et al. Among authors: pyta k. J Med Chem. 2016 Sep 8;59(17):7963-73. doi: 10.1021/acs.jmedchem.6b00764. Epub 2016 Aug 19. J Med Chem. 2016. PMID: 27501415

7

Synthesis, docking and antibacterial studies of more potent amine and hydrazone rifamycin congeners than rifampicin.

Pyta K, Janas A, Szukowska M, Pecyna P, Jaworska M, Gajecka M, Bartl F, Przybylski P. Pyta K, et al. Eur J Med Chem. 2019 Apr 1;167:96-104. doi: 10.1016/j.ejmech.2019.02.009. Epub 2019 Feb 4. Eur J Med Chem. 2019. PMID: 30769243

8

Specific Interactions between Rifamycin Antibiotics and Water Influencing Ability To Overcome Natural Cell Barriers and the Range of Antibacterial Potency.

Pyta K, Janas A, Skrzypczak N, Schilf W, Wicher B, Gdaniec M, Bartl F, Przybylski P. Pyta K, et al. ACS Infect Dis. 2019 Oct 11;5(10):1754-1763. doi: 10.1021/acsinfecdis.9b00176. Epub 2019 Sep 10. ACS Infect Dis. 2019. PMID: 31461259

9

Synthesis, structure and anticancer activity of new geldanamycin amine analogs containing C(17)- or C(20)- flexible and rigid arms as well as closed or open ansa-bridges.

Skrzypczak N, Pyta K, Ruszkowski P, Gdaniec M, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: pyta k. Eur J Med Chem. 2020 Sep 15;202:112624. doi: 10.1016/j.ejmech.2020.112624. Epub 2020 Jul 3. Eur J Med Chem. 2020. PMID: 32663707

10

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators.

Skrzypczak N, Pyta K, Ruszkowski P, Mikołajczak P, Kucińska M, Murias M, Gdaniec M, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: pyta k. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1898-1904. doi: 10.1080/14756366.2021.1960829. J Enzyme Inhib Med Chem. 2021. PMID: 34344239 Free PMC article.

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