Bartl F - Search Results

1

Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity.

Skrzypczak N, Pyta K, Bohusz W, Leśniewska A, Gdaniec M, Ruszkowski P, Schilf W, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: bartl f. J Org Chem. 2023 Jul 7;88(13):9469-9474. doi: 10.1021/acs.joc.3c00493. Epub 2023 Jun 5. J Org Chem. 2023. PMID: 37276434 Free PMC article.

2

Synthesis, docking and antibacterial studies of more potent amine and hydrazone rifamycin congeners than rifampicin.

Pyta K, Janas A, Szukowska M, Pecyna P, Jaworska M, Gajecka M, Bartl F, Przybylski P. Pyta K, et al. Among authors: bartl f. Eur J Med Chem. 2019 Apr 1;167:96-104. doi: 10.1016/j.ejmech.2019.02.009. Epub 2019 Feb 4. Eur J Med Chem. 2019. PMID: 30769243

3

Specific Interactions between Rifamycin Antibiotics and Water Influencing Ability To Overcome Natural Cell Barriers and the Range of Antibacterial Potency.

Pyta K, Janas A, Skrzypczak N, Schilf W, Wicher B, Gdaniec M, Bartl F, Przybylski P. Pyta K, et al. Among authors: bartl f. ACS Infect Dis. 2019 Oct 11;5(10):1754-1763. doi: 10.1021/acsinfecdis.9b00176. Epub 2019 Sep 10. ACS Infect Dis. 2019. PMID: 31461259

4

Synthesis, structure and anticancer activity of new geldanamycin amine analogs containing C(17)- or C(20)- flexible and rigid arms as well as closed or open ansa-bridges.

Skrzypczak N, Pyta K, Ruszkowski P, Gdaniec M, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: bartl f. Eur J Med Chem. 2020 Sep 15;202:112624. doi: 10.1016/j.ejmech.2020.112624. Epub 2020 Jul 3. Eur J Med Chem. 2020. PMID: 32663707

5

Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators.

Skrzypczak N, Pyta K, Ruszkowski P, Mikołajczak P, Kucińska M, Murias M, Gdaniec M, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: bartl f. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1898-1904. doi: 10.1080/14756366.2021.1960829. J Enzyme Inhib Med Chem. 2021. PMID: 34344239 Free PMC article.

6

Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs.

Pyta K, Skrzypczak N, Ruszkowski P, Bartl F, Przybylski P. Pyta K, et al. Among authors: bartl f. J Enzyme Inhib Med Chem. 2022 Dec;37(1):597-605. doi: 10.1080/14756366.2022.2028782. J Enzyme Inhib Med Chem. 2022. PMID: 35067138 Free PMC article.

7

Modifications of geldanamycin via CuAAC altering affinity to chaperone protein Hsp90 and cytotoxicity.

Skrzypczak N, Buczkowski A, Bohusz W, Nowak E, Tokarska K, Leśniewska A, Alzebari AM, Ruszkowski P, Gdaniec M, Bartl F, Przybylski P. Skrzypczak N, et al. Among authors: bartl f. Eur J Med Chem. 2023 Aug 5;256:115450. doi: 10.1016/j.ejmech.2023.115450. Epub 2023 May 12. Eur J Med Chem. 2023. PMID: 37210951 Free article.

8

Regioselective long-range proton transfer in new rifamycin antibiotics: a process in which crown ethers act as stronger Brønsted bases than amines.

Pyta K, Przybylski P, Bartl F. Pyta K, et al. Among authors: bartl f. Chemphyschem. 2015 Apr 7;16(5):938-42. doi: 10.1002/cphc.201402892. Epub 2015 Jan 29. Chemphyschem. 2015. PMID: 25639734

9

16-Membered Macrolide Lactone Derivatives Bearing a Triazole-Functionalized Arm at the Aglycone C13 Position as Antibacterial and Anticancer Agents.

Domagalska J, Janas A, Pyta K, Pecyna P, Ruszkowski P, Celewicz L, Gajecka M, Bartl F, Przybylski P. Domagalska J, et al. Among authors: bartl f. ChemMedChem. 2016 Sep 6;11(17):1886-91. doi: 10.1002/cmdc.201600250. Epub 2016 Jul 14. ChemMedChem. 2016. PMID: 27411730

10

Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.

Huczyñski A, Przybylski P, Brzezinski B, Bartl F. Huczyñski A, et al. Among authors: bartl f. J Phys Chem B. 2006 Aug 10;110(31):15615-23. doi: 10.1021/jp062160o. J Phys Chem B. 2006. PMID: 16884286

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