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Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia.
Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB. Patzek S, et al. Among authors: ornitz dm. iScience. 2023 Mar 25;26(4):106500. doi: 10.1016/j.isci.2023.106500. eCollection 2023 Apr 21. iScience. 2023. PMID: 37096042 Free PMC article.
Resolving the design principles that control postnatal vascular growth and scaling.
Pi D, Braun J, Dutta S, Patra D, Bougaran P, Mompeón A, Ma F, Stock SR, Choi S, García-Ortega L, Pratama MY, Pichardo D, Ramkhelawon B, Benedito R, Bautch VL, Ornitz DM, Goyal Y, Iruela-Arispe ML. Pi D, et al. Among authors: ornitz dm. bioRxiv [Preprint]. 2024 Dec 11:2024.12.10.627758. doi: 10.1101/2024.12.10.627758. bioRxiv. 2024. PMID: 39713449 Free PMC article. Preprint.
Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).
Bodmer NK, Knutsen RH, Roth RA, Castile RM, Brodt MD, Gierasch CM, Broekelmann TJ, Gibson MA, Haspel JA, Lake SP, Koenitzer JR, Brody SL, Silva MJ, Mecham RP, Ornitz DM. Bodmer NK, et al. Among authors: ornitz dm. Dev Dyn. 2024 Feb;253(2):233-254. doi: 10.1002/dvdy.651. Epub 2023 Sep 9. Dev Dyn. 2024. PMID: 37688792 Review.
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway.
Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X. Lee C, et al. Among authors: ornitz dm. Signal Transduct Target Ther. 2023 Aug 18;8(1):305. doi: 10.1038/s41392-023-01539-9. Signal Transduct Target Ther. 2023. PMID: 37591843 Free PMC article.
247 results