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CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells.
Vlassis A, Jensen TL, Mohr M, Jedrzejczyk DJ, Meng X, Kovacs G, Morera-Gómez M, Barghetti A, Muyo Abad S, Baumgartner RF, Natarajan KN, Nielsen LK, Warnecke T, Gill RT. Vlassis A, et al. Among authors: natarajan kn. iScience. 2023 Oct 27;26(12):108287. doi: 10.1016/j.isci.2023.108287. eCollection 2023 Dec 15. iScience. 2023. PMID: 38034357 Free PMC article.
Extensive folding variability between homologous chromosomes in mammalian cells.
Irastorza-Azcarate I, Kukalev A, Kempfer R, Thieme CJ, Mastrobuoni G, Markowski J, Loof G, Sparks TM, Brookes E, Natarajan KN, Sauer S, Fisher AG, Nicodemi M, Ren B, Schwarz RF, Kempa S, Pombo A. Irastorza-Azcarate I, et al. Among authors: natarajan kn. bioRxiv [Preprint]. 2024 May 10:2024.05.08.591087. doi: 10.1101/2024.05.08.591087. bioRxiv. 2024. PMID: 38766012 Free PMC article. Preprint.
Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition.
Petrosius V, Aragon-Fernandez P, Üresin N, Kovacs G, Phlairaharn T, Furtwängler B, Op De Beeck J, Skovbakke SL, Goletz S, Thomsen SF, Keller UAD, Natarajan KN, Porse BT, Schoof EM. Petrosius V, et al. Among authors: natarajan kn. Nat Commun. 2023 Sep 22;14(1):5910. doi: 10.1038/s41467-023-41602-1. Nat Commun. 2023. PMID: 37737208 Free PMC article.
PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation.
Madsen MS, Broekema MF, Madsen MR, Koppen A, Borgman A, Gräwe C, Thomsen EGK, Westland D, Kranendonk MEG, Koerkamp MG, Hamers N, Bonvin AMJJ, Pittol JMR, Natarajan KN, Kersten S, Holstege FCP, Monajemi H, van Mil SWC, Vermeulen M, Kragelund BB, Cassiman D, Mandrup S, Kalkhoven E. Madsen MS, et al. Among authors: natarajan kn. Nat Commun. 2022 Nov 19;13(1):7090. doi: 10.1038/s41467-022-34766-9. Nat Commun. 2022. PMID: 36402763 Free PMC article.
Cell Competition in Carcinogenesis.
Madan E, Palma AM, Vudatha V, Trevino JG, Natarajan KN, Winn RA, Won KJ, Graham TA, Drapkin R, McDonald SAC, Fisher PB, Gogna R. Madan E, et al. Among authors: natarajan kn. Cancer Res. 2022 Dec 16;82(24):4487-4496. doi: 10.1158/0008-5472.CAN-22-2217. Cancer Res. 2022. PMID: 36214625 Free PMC article.
31 results