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Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C. Gozzi GJ, et al. Among authors: uyanik b. Cell Death Differ. 2020 Jan;27(1):117-129. doi: 10.1038/s41418-019-0343-4. Epub 2019 May 8. Cell Death Differ. 2020. PMID: 31068676 Free PMC article.
HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells.
Causse SZ, Marcion G, Chanteloup G, Uyanik B, Boudesco C, Grigorash BB, Douhard R, Dias AMM, Dumetier B, Dondaine L, Gozzi GJ, Moussay E, Paggetti J, Mirjolet C, de Thonel A, Dubrez L, Demidov ON, Gobbo J, Garrido C. Causse SZ, et al. Among authors: uyanik b. Oncogene. 2019 Apr;38(15):2767-2777. doi: 10.1038/s41388-018-0616-2. Epub 2018 Dec 12. Oncogene. 2019. PMID: 30542121
Lactobacillus stress protein GroEL prevents colonic inflammation.
Dias AMM, Douhard R, Hermetet F, Regimbeau M, Lopez TE, Gonzalez D, Masson S, Marcion G, Chaumonnot K, Uyanik B, Causse SZ, Rieu A, Hadi T, Basset C, Chluba J, Grober J, Guzzo J, Neiers F, Ortega-Deballon P, Demidov ON, Lirussi F, Garrido C. Dias AMM, et al. Among authors: uyanik b. J Gastroenterol. 2021 May;56(5):442-455. doi: 10.1007/s00535-021-01774-3. Epub 2021 Mar 29. J Gastroenterol. 2021. PMID: 33782752
Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.
Uyanik B, Goloudina AR, Akbarali A, Grigorash BB, Petukhov AV, Singhal S, Eruslanov E, Chaloyard J, Lagorgette L, Hadi T, Baidyuk EV, Sakai H, Tessarollo L, Ryffel B, Mazur SJ, Lirussi F, Garrido C, Appella E, Demidov ON. Uyanik B, et al. Nat Commun. 2021 Jun 15;12(1):3622. doi: 10.1038/s41467-021-23330-6. Nat Commun. 2021. PMID: 34131120 Free PMC article.
SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties.
Zakharova VV, Magnitov MD, Del Maestro L, Ulianov SV, Glentis A, Uyanik B, Williart A, Karpukhina A, Demidov O, Joliot V, Vassetzky YS, Mège RM, Piel M, Razin SV, Ait-Si-Ali S. Zakharova VV, et al. Among authors: uyanik b. Nucleic Acids Res. 2022 May 6;50(8):4389-4413. doi: 10.1093/nar/gkac234. Nucleic Acids Res. 2022. PMID: 35474385 Free PMC article.
66 results