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From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access.
Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, Ronca SE, Strych U, Thimmiraju SR, Versteeg L, Villar-Mondragon MJ, Wei J, Zhan B, Bottazzi ME. Hotez PJ, et al. Among authors: thimmiraju sr. Expert Rev Vaccines. 2023 Jan-Dec;22(1):495-500. doi: 10.1080/14760584.2023.2217917. Expert Rev Vaccines. 2023. PMID: 37252854 Free article.
A Recombinant Protein XBB.1.5 RBD/Alum/CpG Vaccine Elicits High Neutralizing Antibody Titers against Omicron Subvariants of SARS-CoV-2.
Thimmiraju SR, Adhikari R, Villar MJ, Lee J, Liu Z, Kundu R, Chen YL, Sharma S, Ghei K, Keegan B, Versteeg L, Gillespie PM, Ciciriello A, Islam NY, Poveda C, Uzcategui N, Chen WH, Kimata JT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Pollet J. Thimmiraju SR, et al. Vaccines (Basel). 2023 Oct 1;11(10):1557. doi: 10.3390/vaccines11101557. Vaccines (Basel). 2023. PMID: 37896960 Free PMC article.
A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses.
Thimmiraju SR, Adhikari R, Redd JR, Villar MJ, Lee J, Liu Z, Chen YL, Sharma S, Kaur A, Uzcategui NL, Ronca SE, Chen WH, Kimata JT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Pollet J. Thimmiraju SR, et al. NPJ Vaccines. 2024 Jul 22;9(1):132. doi: 10.1038/s41541-024-00924-x. NPJ Vaccines. 2024. PMID: 39034332 Free PMC article.
The zebrafish as a potential model for vaccine and adjuvant development.
Hotez PJ, Bottazzi ME, Islam NY, Lee J, Pollet J, Poveda C, Strych U, Thimmiraju SR, Uzcategui NL, Versteeg L, Gorelick D. Hotez PJ, et al. Among authors: thimmiraju sr. Expert Rev Vaccines. 2024 Jan-Dec;23(1):535-545. doi: 10.1080/14760584.2024.2345685. Epub 2024 May 9. Expert Rev Vaccines. 2024. PMID: 38664959 Free article. Review.
Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern.
Pollet J, Strych U, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, Thimmiraju SR, Lopez B, Gillespie PM, Ronca S, Kimata JT, Reers M, Paradkar V, Hotez P, Bottazzi ME. Pollet J, et al. Among authors: thimmiraju sr. bioRxiv [Preprint]. 2022 Mar 22:2021.07.06.451353. doi: 10.1101/2021.07.06.451353. bioRxiv. 2022. Update in: Vaccine. 2022 Jun 9;40(26):3655-3663. doi: 10.1016/j.vaccine.2022.05.007 PMID: 34268512 Free PMC article. Updated. Preprint.