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From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access.
Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, Ronca SE, Strych U, Thimmiraju SR, Versteeg L, Villar-Mondragon MJ, Wei J, Zhan B, Bottazzi ME. Hotez PJ, et al. Among authors: chen wh, chen yl. Expert Rev Vaccines. 2023 Jan-Dec;22(1):495-500. doi: 10.1080/14760584.2023.2217917. Expert Rev Vaccines. 2023. PMID: 37252854 Free article.
Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate.
Chen WH, Pollet J, Strych U, Lee J, Liu Z, Kundu RT, Versteeg L, Villar MJ, Adhikari R, Wei J, Poveda C, Keegan B, Bailey AO, Chen YL, Gillespie PM, Kimata JT, Zhan B, Hotez PJ, Bottazzi ME. Chen WH, et al. Among authors: chen yl. Protein Expr Purif. 2022 Feb;190:106003. doi: 10.1016/j.pep.2021.106003. Epub 2021 Oct 21. Protein Expr Purif. 2022. PMID: 34688919 Free PMC article.
Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-cells.
Poveda C, Leão AC, Mancino C, Taraballi F, Chen YL, Adhikari R, Villar MJ, Kundu R, Nguyen DM, Versteeg L, Strych U, Hotez PJ, Bottazzi ME, Pollet J, Jones KM. Poveda C, et al. Among authors: chen yl. Curr Res Immunol. 2023 Jul 20;4:100066. doi: 10.1016/j.crimmu.2023.100066. eCollection 2023. Curr Res Immunol. 2023. PMID: 37534309 Free PMC article.
A Recombinant Protein XBB.1.5 RBD/Alum/CpG Vaccine Elicits High Neutralizing Antibody Titers against Omicron Subvariants of SARS-CoV-2.
Thimmiraju SR, Adhikari R, Villar MJ, Lee J, Liu Z, Kundu R, Chen YL, Sharma S, Ghei K, Keegan B, Versteeg L, Gillespie PM, Ciciriello A, Islam NY, Poveda C, Uzcategui N, Chen WH, Kimata JT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Pollet J. Thimmiraju SR, et al. Among authors: chen wh, chen yl. Vaccines (Basel). 2023 Oct 1;11(10):1557. doi: 10.3390/vaccines11101557. Vaccines (Basel). 2023. PMID: 37896960 Free PMC article.
A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses.
Thimmiraju SR, Adhikari R, Redd JR, Villar MJ, Lee J, Liu Z, Chen YL, Sharma S, Kaur A, Uzcategui NL, Ronca SE, Chen WH, Kimata JT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Pollet J. Thimmiraju SR, et al. Among authors: chen wh, chen yl. NPJ Vaccines. 2024 Jul 22;9(1):132. doi: 10.1038/s41541-024-00924-x. NPJ Vaccines. 2024. PMID: 39034332 Free PMC article.
4,440 results