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Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance.
Chu Y, Dai E, Li Y, Han G, Pei G, Ingram DR, Thakkar K, Qin JJ, Dang M, Le X, Hu C, Deng Q, Sinjab A, Gupta P, Wang R, Hao D, Peng F, Yan X, Liu Y, Song S, Zhang S, Heymach JV, Reuben A, Elamin YY, Pizzi MP, Lu Y, Lazcano R, Hu J, Li M, Curran M, Futreal A, Maitra A, Jazaeri AA, Ajani JA, Swanton C, Cheng XD, Abbas HA, Gillison M, Bhat K, Lazar AJ, Green M, Litchfield K, Kadara H, Yee C, Wang L. Chu Y, et al. Among authors: wang l, wang r. Nat Med. 2023 Jun;29(6):1550-1562. doi: 10.1038/s41591-023-02371-y. Epub 2023 May 29. Nat Med. 2023. PMID: 37248301 Free PMC article.
Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.
Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, Chen R, Li J, Karpinets T, Khairullah R, Kadara H, Behrens C, Sepesi B, Wang R, Zhu M, Wang L, Vaporciyan A, Roth J, Swisher S, Haymaker C, Zhang J, Wang J, Wong KK, Byers LA, Bernatchez C, Zhang J, Wistuba II, Gibbons DL, Akbay EA, Heymach JV. Le X, et al. Among authors: wang l, wang j, wang r. J Thorac Oncol. 2021 Apr;16(4):583-600. doi: 10.1016/j.jtho.2020.12.010. Epub 2020 Dec 31. J Thorac Oncol. 2021. PMID: 33388477 Free PMC article.
The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.
Hao D, Han G, Sinjab A, Gomez-Bolanos LI, Lazcano R, Serrano A, Hernandez SD, Dai E, Cao X, Hu J, Dang M, Wang R, Chu Y, Song X, Zhang J, Parra ER, Wargo JA, Swisher SG, Cascone T, Sepesi B, Futreal AP, Li M, Dubinett SM, Fujimoto J, Solis Soto LM, Wistuba II, Stevenson CS, Spira A, Shalapour S, Kadara H, Wang L. Hao D, et al. Among authors: wang l, wang r. Cancer Discov. 2022 Nov 2;12(11):2626-2645. doi: 10.1158/2159-8290.CD-21-1658. Cancer Discov. 2022. PMID: 36098652 Free PMC article.
A new intronic quantitative PCR method led to the discovery of transformation from human ascites to murine malignancy in a mouse model.
Jin J, Huo L, Fan Y, Wang R, Scott AW, Pizzi MP, Yao X, Shao S, Ma L, Da Silva MS, Yamashita K, Yoshimura K, Zhang B, Wu J, Wang L, Song S, Ajani JA. Jin J, et al. Among authors: wang l, wang r. Front Oncol. 2023 Feb 6;13:1062424. doi: 10.3389/fonc.2023.1062424. eCollection 2023. Front Oncol. 2023. PMID: 36865791 Free PMC article.
Proteogenomic landscape of gastric adenocarcinoma peritoneal metastases.
Zhao S, Wang R, Song S, Hao D, Han G, Song X, Zhang J, Pizzi MP, Shanbhag N, Futreal A, Badgwell B, Harada K, Calin G, Vykoukal J, Yu CY, Katayama H, Hanash SM, Wang L, Ajani JA. Zhao S, et al. Among authors: wang l, wang r. iScience. 2023 May 19;26(6):106913. doi: 10.1016/j.isci.2023.106913. eCollection 2023 Jun 16. iScience. 2023. PMID: 37305699 Free PMC article.
Single cell clonotypic and transcriptional evolution of multiple myeloma precursor disease.
Dang M, Wang R, Lee HC, Patel KK, Becnel MR, Han G, Thomas SK, Hao D, Chu Y, Weber DM, Lin P, Lutter-Berka Z, Berrios Nolasco DA, Huang M, Bansal H, Song X, Zhang J, Futreal A, Moreno Rueda LY, Symer DE, Green MR, Rojas Hernandez CM, Kroll M, Afshar-Khargan V, Ndacayisaba LJ, Kuhn P, Neelapu SS, Orlowski RZ, Wang L, Manasanch EE. Dang M, et al. Among authors: wang l, wang r. Cancer Cell. 2023 Jun 12;41(6):1032-1047.e4. doi: 10.1016/j.ccell.2023.05.007. Cancer Cell. 2023. PMID: 37311413 Free PMC article.
Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression.
Wang R, Song S, Qin J, Yoshimura K, Peng F, Chu Y, Li Y, Fan Y, Jin J, Dang M, Dai E, Pei G, Han G, Hao D, Li Y, Chatterjee D, Harada K, Pizzi MP, Scott AW, Tatlonghari G, Yan X, Xu Z, Hu C, Mo S, Shanbhag N, Lu Y, Sewastjanow-Silva M, Fouad Abdelhakeem AA, Peng G, Hanash SM, Calin GA, Yee C, Mazur P, Marsden AN, Futreal A, Wang Z, Cheng X, Ajani JA, Wang L. Wang R, et al. Among authors: wang l, wang z. Cancer Cell. 2023 Aug 14;41(8):1407-1426.e9. doi: 10.1016/j.ccell.2023.06.005. Epub 2023 Jul 6. Cancer Cell. 2023. PMID: 37419119 Free PMC article.
Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response.
Cheng X, Dai E, Wu J, Flores NM, Chu Y, Wang R, Dang M, Xu Z, Han G, Liu Y, Chatterjee D, Hu C, Ying J, Du Y, Yang L, Guan X, Mo S, Cao X, Pei G, Jiang J, Lu X, Benitez AM, Waters RE, Pizzi MP, Shanbhag N, Fan Y, Peng F, Hanash SM, Calin G, Futreal A, Song S, Yee C, Mazur PK, Qin JJ, Ajani JA, Wang L. Cheng X, et al. Among authors: wang l, wang r. Gastroenterology. 2024 Dec;167(7):1345-1357. doi: 10.1053/j.gastro.2024.07.038. Epub 2024 Aug 2. Gastroenterology. 2024. PMID: 39097198
METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics.
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y, Czerniak BA, Futreal A, Maitra A, Lazar A, Kadara H, Jazaeri AA, Cheng X, Ajani J, Gao J, Hu J, Wang L. Jiang J, et al. Among authors: wang l, wang r. Nat Commun. 2024 Aug 25;15(1):7312. doi: 10.1038/s41467-024-51708-9. Nat Commun. 2024. PMID: 39181865 Free PMC article.
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