Zhang J - Search Results

1

Novel Medicinal Chemistry Strategies Targeting CDK5 for Drug Discovery.

Tang W, Lin C, Yu Q, Zhang D, Liu Y, Zhang L, Zhou Z, Zhang J, Ouyang L. Tang W, et al. Among authors: zhang l, zhang d, zhang j. J Med Chem. 2023 Jun 8;66(11):7140-7161. doi: 10.1021/acs.jmedchem.3c00566. Epub 2023 May 26. J Med Chem. 2023. PMID: 37234044 Review.

2

Targeting autophagy-related protein kinases for potential therapeutic purpose.

Xiang H, Zhang J, Lin C, Zhang L, Liu B, Ouyang L. Xiang H, et al. Among authors: zhang l, zhang j. Acta Pharm Sin B. 2020 Apr;10(4):569-581. doi: 10.1016/j.apsb.2019.10.003. Epub 2019 Oct 18. Acta Pharm Sin B. 2020. PMID: 32322463 Free PMC article. Review.

3

Proteolysis-targeting chimeras in breast cancer therapy.

Zhang J, Ouyang L. Zhang J, et al. Future Med Chem. 2020 Dec;12(24):2175-2177. doi: 10.4155/fmc-2020-0279. Epub 2020 Nov 23. Future Med Chem. 2020. PMID: 33225735 Review. No abstract available.

4

Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy.

Yang C, Zhang J, Liao M, Yang Y, Wang Y, Yuan Y, Ouyang L. Yang C, et al. Among authors: zhang j. Drug Discov Today. 2021 Mar;26(3):817-825. doi: 10.1016/j.drudis.2020.12.006. Epub 2020 Dec 11. Drug Discov Today. 2021. PMID: 33316375 Review.

5

Targeting Bromodomain and Extraterminal Proteins for Drug Discovery: From Current Progress to Technological Development.

Tang P, Zhang J, Liu J, Chiang CM, Ouyang L. Tang P, et al. Among authors: zhang j. J Med Chem. 2021 Mar 11;64(5):2419-2435. doi: 10.1021/acs.jmedchem.0c01487. Epub 2021 Feb 22. J Med Chem. 2021. PMID: 33616410 Free PMC article. Review.

6

Targeting Lysosomal Degradation Pathways: New Strategies and Techniques for Drug Discovery.

Pei J, Wang G, Feng L, Zhang J, Jiang T, Sun Q, Ouyang L. Pei J, et al. Among authors: zhang j. J Med Chem. 2021 Apr 8;64(7):3493-3507. doi: 10.1021/acs.jmedchem.0c01689. Epub 2021 Mar 25. J Med Chem. 2021. PMID: 33764774 Review.

7

Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.

Xu T, Zhang J, Yang C, Pluta R, Wang G, Ye T, Ouyang L. Xu T, et al. Among authors: zhang j. Eur J Med Chem. 2021 Jul 5;219:113424. doi: 10.1016/j.ejmech.2021.113424. Epub 2021 Apr 3. Eur J Med Chem. 2021. PMID: 33862514

8

Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast Cancer.

Li Y, Yang G, Zhang J, Tang P, Yang C, Wang G, Chen J, Liu J, Zhang L, Ouyang L. Li Y, et al. Among authors: zhang l, zhang j. J Med Chem. 2021 Aug 26;64(16):12022-12048. doi: 10.1021/acs.jmedchem.1c00678. Epub 2021 Aug 5. J Med Chem. 2021. PMID: 34351741

9

Targeting Autophagy-Related Epigenetic Regulators for Cancer Drug Discovery.

Li Y, Yang G, Yang C, Tang P, Chen J, Zhang J, Liu J, Ouyang L. Li Y, et al. Among authors: zhang j. J Med Chem. 2021 Aug 26;64(16):11798-11815. doi: 10.1021/acs.jmedchem.1c00579. Epub 2021 Aug 11. J Med Chem. 2021. PMID: 34378389

10

Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.

Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B. Zhang J, et al. Among authors: zhang l. J Med Chem. 2021 Oct 14;64(19):14192-14216. doi: 10.1021/acs.jmedchem.0c02268. Epub 2021 Oct 3. J Med Chem. 2021. PMID: 34605238

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