Mittag T - Search Results

1

Phase Separation in Mixtures of Prion-Like Low Complexity Domains is Driven by the Interplay of Homotypic and Heterotypic Interactions.

Pappu R, Farag M, Borcherds W, Bremer A, Mittag T. Pappu R, et al. Among authors: mittag t. Res Sq [Preprint]. 2023 May 4:rs.3.rs-2870258. doi: 10.21203/rs.3.rs-2870258/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Sep 8;14(1):5527. doi: 10.1038/s41467-023-41274-x PMID: 37205474 Free PMC article. Updated. Preprint.

2

Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation.

Martin EW, Holehouse AS, Grace CR, Hughes A, Pappu RV, Mittag T. Martin EW, et al. Among authors: mittag t. J Am Chem Soc. 2016 Nov 30;138(47):15323-15335. doi: 10.1021/jacs.6b10272. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27807972 Free PMC article.

3

Phase separation in biology and disease-a symposium report.

Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL. Cable J, et al. Among authors: mittag t. Ann N Y Acad Sci. 2019 Sep;1452(1):3-11. doi: 10.1111/nyas.14126. Epub 2019 Jun 14. Ann N Y Acad Sci. 2019. PMID: 31199001 Free PMC article.

4

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains.

Martin EW, Holehouse AS, Peran I, Farag M, Incicco JJ, Bremer A, Grace CR, Soranno A, Pappu RV, Mittag T. Martin EW, et al. Among authors: mittag t. Science. 2020 Feb 7;367(6478):694-699. doi: 10.1126/science.aaw8653. Science. 2020. PMID: 32029630 Free PMC article.

5

Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins.

Zeng X, Holehouse AS, Chilkoti A, Mittag T, Pappu RV. Zeng X, et al. Among authors: mittag t. Biophys J. 2020 Jul 21;119(2):402-418. doi: 10.1016/j.bpj.2020.06.014. Epub 2020 Jun 23. Biophys J. 2020. PMID: 32619404 Free PMC article.

6

Microfluidic characterization of macromolecular liquid-liquid phase separation.

Bremer A, Mittag T, Heymann M. Bremer A, et al. Among authors: mittag t. Lab Chip. 2020 Nov 10;20(22):4225-4234. doi: 10.1039/d0lc00613k. Lab Chip. 2020. PMID: 33057557 Free PMC article.

7

How do intrinsically disordered protein regions encode a driving force for liquid-liquid phase separation?

Borcherds W, Bremer A, Borgia MB, Mittag T. Borcherds W, et al. Among authors: mittag t. Curr Opin Struct Biol. 2021 Apr;67:41-50. doi: 10.1016/j.sbi.2020.09.004. Epub 2020 Oct 15. Curr Opin Struct Biol. 2021. PMID: 33069007 Free PMC article. Review.

8

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins.

Lazar T, Martínez-Pérez E, Quaglia F, Hatos A, Chemes LB, Iserte JA, Méndez NA, Garrone NA, Saldaño TE, Marchetti J, Rueda AJV, Bernadó P, Blackledge M, Cordeiro TN, Fagerberg E, Forman-Kay JD, Fornasari MS, Gibson TJ, Gomes GW, Gradinaru CC, Head-Gordon T, Jensen MR, Lemke EA, Longhi S, Marino-Buslje C, Minervini G, Mittag T, Monzon AM, Pappu RV, Parisi G, Ricard-Blum S, Ruff KM, Salladini E, Skepö M, Svergun D, Vallet SD, Varadi M, Tompa P, Tosatto SCE, Piovesan D. Lazar T, et al. Among authors: mittag t. Nucleic Acids Res. 2021 Jan 8;49(D1):D404-D411. doi: 10.1093/nar/gkaa1021. Nucleic Acids Res. 2021. PMID: 33305318 Free PMC article.

9

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation.

Martin EW, Thomasen FE, Milkovic NM, Cuneo MJ, Grace CR, Nourse A, Lindorff-Larsen K, Mittag T. Martin EW, et al. Among authors: mittag t. Nucleic Acids Res. 2021 Mar 18;49(5):2931-2945. doi: 10.1093/nar/gkab063. Nucleic Acids Res. 2021. PMID: 33577679 Free PMC article.

10

Deciphering how naturally occurring sequence features impact the phase behaviours of disordered prion-like domains.

Bremer A, Farag M, Borcherds WM, Peran I, Martin EW, Pappu RV, Mittag T. Bremer A, et al. Among authors: mittag t. Nat Chem. 2022 Feb;14(2):196-207. doi: 10.1038/s41557-021-00840-w. Epub 2021 Dec 20. Nat Chem. 2022. PMID: 34931046 Free PMC article.

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