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DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates.
Qu P, Rom O, Li K, Jia L, Gao X, Liu Z, Ding S, Zhao M, Wang H, Chen S, Xiong X, Zhao Y, Xue C, Zhao Y, Chu C, Wen B, Finney AC, Zheng Z, Cao W, Zhao J, Bai L, Zhao S, Sun D, Zeng R, Lin J, Liu W, Zheng L, Zhang J, Liu E, Chen YE. Qu P, et al. Among authors: rom o. Cell Metab. 2023 May 2;35(5):742-757.e10. doi: 10.1016/j.cmet.2023.03.013. Epub 2023 Apr 10. Cell Metab. 2023. PMID: 37040763 Free article.
Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.
Zhao Y, Liu Y, Zhao G, Lu H, Liu Y, Xue C, Chang Z, Liu H, Deng Y, Liang W, Wang H, Rom O, Garcia-Barrio MT, Zhu T, Guo Y, Chang L, Lin J, Chen YE, Zhang J. Zhao Y, et al. Among authors: rom o. Cell Rep. 2023 Oct 31;42(10):113171. doi: 10.1016/j.celrep.2023.113171. Epub 2023 Sep 27. Cell Rep. 2023. PMID: 37768825 Free PMC article.
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis.
Das S, Finney AC, Anand SK, Rohilla S, Liu Y, Pandey N, Ghrayeb A, Kumar D, Nunez K, Liu Z, Arias F, Zhao Y, Pearson-Gallion BH, McKinney MP, Richard KSE, Gomez-Vidal JA, Abdullah CS, Cockerham ED, Eniafe J, Yurochko AD, Magdy T, Pattillo CB, Kevil CG, Razani B, Bhuiyan MS, Seeley EH, Galliano GE, Wei B, Tan L, Mahmud I, Surakka I, Garcia-Barrio MT, Lorenzi PL, Gottlieb E, Salido E, Zhang J, Orr AW, Liu W, Diaz-Gavilan M, Chen YE, Dhanesha N, Thevenot PT, Cohen AJ, Yurdagul A Jr, Rom O. Das S, et al. Among authors: rom o. Nat Metab. 2024 Oct;6(10):1939-1962. doi: 10.1038/s42255-024-01134-4. Epub 2024 Sep 27. Nat Metab. 2024. PMID: 39333384 Free PMC article.
Enhanced venous thrombosis and hypercoagulability in murine and human metabolic dysfunction-associated steatohepatitis.
Pandey N, Anand SK, Kaur H, Richard KSE, Chandaluri L, Butler ME, Zhang X, Pearson-Gallion B, Rohilla S, Das S, Magdy T, Sethu P, Núñez KG, Orr AW, Stokes KY, Thevenot PT, Cohen AJ, Rom O, Dhanesha N. Pandey N, et al. Among authors: rom o. J Thromb Haemost. 2024 Dec;22(12):3572-3580. doi: 10.1016/j.jtha.2024.08.023. Epub 2024 Sep 19. J Thromb Haemost. 2024. PMID: 39306095
Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT.
Pandey N, Kaur H, Chorawala MR, Anand SK, Chandaluri L, Butler ME, Aishwarya R, Gaddam SJ, Shen X, Alfaidi M, Wang J, Zhang X, Beedupalli K, Bhuiyan MS, Bhuiyan MAN, Buchhanolla P, Rai P, Shah R, Chokhawala H, Jordan JD, Magdy T, Orr AW, Stokes KY, Rom O, Dhanesha N. Pandey N, et al. Among authors: rom o. Blood Adv. 2024 May 14;8(9):2104-2117. doi: 10.1182/bloodadvances.2023012282. Blood Adv. 2024. PMID: 38498701 Free PMC article.
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Zhang X, Kapoor D, Jeong SJ, Fappi A, Stitham J, Shabrish V, Sergin I, Yousif E, Rodriguez-Velez A, Yeh YS, Park A, Yurdagul A Jr, Rom O, Epelman S, Schilling JD, Sardiello M, Diwan A, Cho J, Stitziel NO, Javaheri A, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: rom o. Nat Metab. 2024 Feb;6(2):359-377. doi: 10.1038/s42255-024-00984-2. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409323 Free PMC article.
69 results