Botas J - Search Results

1

Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.

Yu M, Ye H, De-Paula RB, Mangleburg CG, Wu T, Lee TV, Li Y, Duong D, Phillips B, Cruchaga C, Allen GI, Seyfried NT, Al-Ramahi I, Botas J, Shulman JM. Yu M, et al. Among authors: botas j. PLoS Genet. 2023 May 18;19(5):e1010760. doi: 10.1371/journal.pgen.1010760. eCollection 2023 May. PLoS Genet. 2023. PMID: 37200393 Free PMC article.

2

Gene-dose titration analysis in the search of trans-regulatory genes in Drosophila.

Botas J, Moscoso del Prado J, García-Bellido A. Botas J, et al. EMBO J. 1982;1(3):307-10. doi: 10.1002/j.1460-2075.1982.tb01165.x. EMBO J. 1982. PMID: 7188185 Free PMC article.

3

Negative autoregulation by Ultrabithorax controls the level and pattern of its expression.

Irvine KD, Botas J, Jha S, Mann RS, Hogness DS. Irvine KD, et al. Among authors: botas j. Development. 1993 Jan;117(1):387-99. doi: 10.1242/dev.117.1.387. Development. 1993. PMID: 7900988

4

Direct regulation of the muscle-identity gene apterous by a Hox protein in the somatic mesoderm.

Capovilla M, Kambris Z, Botas J. Capovilla M, et al. Among authors: botas j. Development. 2001 Apr;128(8):1221-30. doi: 10.1242/dev.128.8.1221. Development. 2001. PMID: 11262224

5

The mechanism of Golgi segregation during mitosis is cell type-specific.

Stanley H, Botas J, Malhotra V. Stanley H, et al. Among authors: botas j. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14467-70. doi: 10.1073/pnas.94.26.14467. Proc Natl Acad Sci U S A. 1997. PMID: 9405636 Free PMC article.

6

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

Chan SK, Jaffe L, Capovilla M, Botas J, Mann RS. Chan SK, et al. Among authors: botas j. Cell. 1994 Aug 26;78(4):603-15. doi: 10.1016/0092-8674(94)90525-8. Cell. 1994. PMID: 7915199

7

MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1.

de Haro M, Al-Ramahi I, De Gouyon B, Ukani L, Rosa A, Faustino NA, Ashizawa T, Cooper TA, Botas J. de Haro M, et al. Among authors: botas j. Hum Mol Genet. 2006 Jul 1;15(13):2138-45. doi: 10.1093/hmg/ddl137. Epub 2006 May 24. Hum Mol Genet. 2006. PMID: 16723374

8

CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.

Al-Ramahi I, Lam YC, Chen HK, de Gouyon B, Zhang M, Pérez AM, Branco J, de Haro M, Patterson C, Zoghbi HY, Botas J. Al-Ramahi I, et al. Among authors: botas j. J Biol Chem. 2006 Sep 8;281(36):26714-24. doi: 10.1074/jbc.M601603200. Epub 2006 Jul 10. J Biol Chem. 2006. PMID: 16831871 Free article.

9

Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases.

Branco J, Al-Ramahi I, Ukani L, Pérez AM, Fernandez-Funez P, Rincón-Limas D, Botas J. Branco J, et al. Among authors: botas j. Hum Mol Genet. 2008 Feb 1;17(3):376-90. doi: 10.1093/hmg/ddm315. Epub 2007 Nov 5. Hum Mol Genet. 2008. PMID: 17984172

10

dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1.

Al-Ramahi I, Pérez AM, Lim J, Zhang M, Sorensen R, de Haro M, Branco J, Pulst SM, Zoghbi HY, Botas J. Al-Ramahi I, et al. Among authors: botas j. PLoS Genet. 2007 Dec 28;3(12):e234. doi: 10.1371/journal.pgen.0030234. Epub 2007 Nov 16. PLoS Genet. 2007. PMID: 18166084 Free PMC article.

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