Chlon T - Search Results

1

Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms.

Badar T, Nanaa A, Foran JM, Viswanatha D, Al-Kali A, Lasho T, Finke C, Alkhateeb HB, He R, Gangat N, Shah M, Tefferi A, Mangaonkar AA, Litzow MR, Ongie LJ, Chlon T, Ferrer A, Patnaik MM. Badar T, et al. Among authors: chlon t. Haematologica. 2023 Nov 1;108(11):3033-3043. doi: 10.3324/haematol.2023.282867. Haematologica. 2023. PMID: 37199125 Free PMC article. Review.

2

Germline and Somatic Defects in DDX41 and its Impact on Myeloid Neoplasms.

Badar T, Chlon T. Badar T, et al. Among authors: chlon t. Curr Hematol Malig Rep. 2022 Oct;17(5):113-120. doi: 10.1007/s11899-022-00667-3. Epub 2022 Jul 4. Curr Hematol Malig Rep. 2022. PMID: 35781188 Free PMC article. Review.

3

Global transcriptome and chromatin occupancy analysis reveal the short isoform of GATA1 is deficient for erythroid specification and gene expression.

Chlon TM, McNulty M, Goldenson B, Rosinski A, Crispino JD. Chlon TM, et al. Haematologica. 2015 May;100(5):575-84. doi: 10.3324/haematol.2014.112714. Epub 2015 Feb 14. Haematologica. 2015. PMID: 25682601 Free PMC article.

4

Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia.

Chlon TM, Stepanchick E, Hershberger CE, Daniels NJ, Hueneman KM, Kuenzi Davis A, Choi K, Zheng Y, Gurnari C, Haferlach T, Padgett RA, Maciejewski JP, Starczynowski DT. Chlon TM, et al. Cell Stem Cell. 2021 Nov 4;28(11):1966-1981.e6. doi: 10.1016/j.stem.2021.08.004. Epub 2021 Sep 1. Cell Stem Cell. 2021. PMID: 34473945 Free PMC article.

5

Chronic immune response dysregulation in MDS pathogenesis.

Barreyro L, Chlon TM, Starczynowski DT. Barreyro L, et al. Among authors: chlon tm. Blood. 2018 Oct 11;132(15):1553-1560. doi: 10.1182/blood-2018-03-784116. Epub 2018 Aug 13. Blood. 2018. PMID: 30104218 Free PMC article. Review.

6

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling.

Malinge S, Thiollier C, Chlon TM, Doré LC, Diebold L, Bluteau O, Mabialah V, Vainchenker W, Dessen P, Winandy S, Mercher T, Crispino JD. Malinge S, et al. Among authors: chlon tm. Blood. 2013 Mar 28;121(13):2440-51. doi: 10.1182/blood-2012-08-450627. Epub 2013 Jan 18. Blood. 2013. PMID: 23335373 Free PMC article.

7

Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes.

Malinge S, Chlon T, Doré LC, Ketterling RP, Tallman MS, Paietta E, Gamis AS, Taub JW, Chou ST, Weiss MJ, Crispino JD, Figueroa ME. Malinge S, et al. Among authors: chlon t. Blood. 2013 Oct 3;122(14):e33-43. doi: 10.1182/blood-2013-05-503011. Epub 2013 Aug 26. Blood. 2013. PMID: 23980066 Free PMC article.

8

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.

Malinge S, Bliss-Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, Crispino JD. Malinge S, et al. Among authors: chlon t. J Clin Invest. 2012 Mar;122(3):948-62. doi: 10.1172/JCI60455. Epub 2012 Feb 22. J Clin Invest. 2012. PMID: 22354171 Free PMC article.

9

Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.

Doré LC, Chlon TM, Brown CD, White KP, Crispino JD. Doré LC, et al. Blood. 2012 Apr 19;119(16):3724-33. doi: 10.1182/blood-2011-09-380634. Epub 2012 Mar 1. Blood. 2012. PMID: 22383799 Free PMC article.

10

Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression.

Chlon TM, Doré LC, Crispino JD. Chlon TM, et al. Mol Cell. 2012 Aug 24;47(4):608-21. doi: 10.1016/j.molcel.2012.05.051. Epub 2012 Jul 5. Mol Cell. 2012. PMID: 22771118 Free PMC article.

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