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BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes.
Xu R, Wang K, Yao Z, Zhang Y, Jin L, Pang J, Zhou Y, Wang K, Liu D, Zhang Y, Sun P, Wang F, Chang X, Liu T, Wang S, Zhang Y, Lin S, Hu C, Zhu Y, Han X. Xu R, et al. Among authors: lin s. J Mol Cell Biol. 2023 Nov 27;15(5):mjad033. doi: 10.1093/jmcb/mjad033. J Mol Cell Biol. 2023. PMID: 37188647 Free PMC article.
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Li TY, Sun Y, Liang Y, Liu Q, Shi Y, Zhang CS, Zhang C, Song L, Zhang P, Zhang X, Li X, Chen T, Huang HY, He X, Wang Y, Wu YQ, Chen S, Jiang M, Chen C, Xie C, Yang JY, Lin Y, Zhao S, Ye Z, Lin SY, Chiu DT, Lin SC. Li TY, et al. Among authors: lin sy, lin y, lin sc. Mol Cell. 2016 May 5;62(3):359-370. doi: 10.1016/j.molcel.2016.04.009. Mol Cell. 2016. PMID: 27153534 Free article.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC. Shi M, et al. Nat Cell Biol. 2021 Mar;23(3):268-277. doi: 10.1038/s41556-021-00642-9. Epub 2021 Mar 4. Nat Cell Biol. 2021. PMID: 33664495
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Wu YQ, Zhang CS, Xiong J, Cai DQ, Wang CZ, Wang Y, Liu YH, Wang Y, Li Y, Wu J, Wu J, Lan B, Wang X, Chen S, Cao X, Wei X, Hu HH, Guo H, Yu Y, Ghafoor A, Xie C, Wu Y, Xu Z, Zhang C, Zhu M, Huang X, Sun X, Lin SY, Piao HL, Zhou J, Lin SC. Wu YQ, et al. Among authors: lin sy, lin sc. Cell Res. 2023 Nov;33(11):835-850. doi: 10.1038/s41422-023-00874-4. Epub 2023 Sep 19. Cell Res. 2023. PMID: 37726403 Free PMC article.
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Wu HM, Yang YV, Huang NJ, Fan LP, Dai YY, Hu KT, Tang TY, Liu L, Xu Y, Liu DT, Cai ZX, Niu XY, Ren XY, Yao ZH, Qin HY, Chen JZ, Huang X, Zhang C, You X, Wang C, He Y, Hong W, Sun YX, Zhan YH, Lin SY. Wu HM, et al. Front Neurosci. 2024 Apr 23;18:1368552. doi: 10.3389/fnins.2024.1368552. eCollection 2024. Front Neurosci. 2024. PMID: 38716255 Free PMC article.
HuR promotes triglyceride synthesis and intestinal fat absorption.
Liu C, Lin Y, Wang Y, Lin S, Zhou J, Tang H, Yi X, Ma Z, Xia T, Jiang B, Tian F, Ju Z, Liu B, Gu X, Yang Z, Wang W. Liu C, et al. Among authors: lin s, lin y. Cell Rep. 2024 May 28;43(5):114238. doi: 10.1016/j.celrep.2024.114238. Epub 2024 May 14. Cell Rep. 2024. PMID: 38748875 Free article.
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