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A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma.
Salcher S, Spoden G, Hagenbuchner J, Führer S, Kaserer T, Tollinger M, Huber-Cantonati P, Gruber T, Schuster D, Gust R, Zwierzina H, Müller T, Kiechl-Kohlendorfer U, Ausserlechner MJ, Obexer P. Salcher S, et al. Among authors: kaserer t. Oncogene. 2020 Jan;39(5):1080-1097. doi: 10.1038/s41388-019-1044-7. Epub 2019 Oct 7. Oncogene. 2020. PMID: 31591479 Free PMC article.
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules.
Hagenbuchner J, Obsilova V, Kaserer T, Kaiser N, Rass B, Psenakova K, Docekal V, Alblova M, Kohoutova K, Schuster D, Aneichyk T, Vesely J, Obexer P, Obsil T, Ausserlechner MJ. Hagenbuchner J, et al. Among authors: kaserer t. Elife. 2019 Dec 4;8:e48876. doi: 10.7554/eLife.48876. Elife. 2019. PMID: 31789593 Free PMC article.
38 results