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Page 1
CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T; 23andMe Research Team; Mackillop J, Stephens DN, Elson SL, Fontanillas P, Khokhar JY, Young JW, Palmer AA. Sanchez-Roige S, et al. Among authors: jennings mv. Transl Psychiatry. 2023 May 12;13(1):167. doi: 10.1038/s41398-023-02453-y. Transl Psychiatry. 2023. PMID: 37173343 Free PMC article.
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.
Mallard TT, Savage JE, Johnson EC, Huang Y, Edwards AC, Hottenga JJ, Grotzinger AD, Gustavson DE, Jennings MV, Anokhin A, Dick DM, Edenberg HJ, Kramer JR, Lai D, Meyers JL, Pandey AK, Harden KP, Nivard MG, de Geus EJC, Boomsma DI, Agrawal A, Davis LK, Clarke TK, Palmer AA, Sanchez-Roige S. Mallard TT, et al. Among authors: jennings mv. Am J Psychiatry. 2022 Jan;179(1):58-70. doi: 10.1176/appi.ajp.2020.20091390. Epub 2021 May 14. Am J Psychiatry. 2022. PMID: 33985350 Free PMC article.
Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry.
Sanchez-Roige S, Fontanillas P, Jennings MV, Bianchi SB, Huang Y, Hatoum AS, Sealock J, Davis LK, Elson SL; 23andMe Research Team; Palmer AA. Sanchez-Roige S, et al. Among authors: jennings mv. Mol Psychiatry. 2021 Nov;26(11):6209-6217. doi: 10.1038/s41380-021-01335-3. Epub 2021 Nov 2. Mol Psychiatry. 2021. PMID: 34728798 Free PMC article.
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.
Deak JD, Zhou H, Galimberti M, Levey DF, Wendt FR, Sanchez-Roige S, Hatoum AS, Johnson EC, Nunez YZ, Demontis D, Børglum AD, Rajagopal VM, Jennings MV, Kember RL, Justice AC, Edenberg HJ, Agrawal A, Polimanti R, Kranzler HR, Gelernter J. Deak JD, et al. Among authors: jennings mv. Mol Psychiatry. 2022 Oct;27(10):3970-3979. doi: 10.1038/s41380-022-01709-1. Epub 2022 Jul 25. Mol Psychiatry. 2022. PMID: 35879402 Free PMC article.
Identifying High-Risk Comorbidities Associated with Opioid Use Patterns Using Electronic Health Record Prescription Data.
Jennings MV, Lee H, Rocha DB, Bianchi SB, Coombes BJ, Crist RC, Faucon AB, Hu Y, Kember RL, Mallard TT, Niarchou M, Poulsen MN, Straub P, Urman RD, Walsh CG, Davis LK, Smoller JW, Troiani V, Sanchez-Roige S. Jennings MV, et al. Complex Psychiatry. 2022 Sep;8(1-2):47-55. doi: 10.1159/000525313. Epub 2022 Jun 2. Complex Psychiatry. 2022. PMID: 36545045 Free PMC article.
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. Toikumo S, et al. Among authors: jennings mv. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. medRxiv. 2023. Update in: Nat Hum Behav. 2024 Jun;8(6):1177-1193. doi: 10.1038/s41562-024-01851-6 PMID: 37034728 Free PMC article. Updated. Preprint.
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.
Hatoum AS, Colbert SMC, Johnson EC, Huggett SB, Deak JD, Pathak G, Jennings MV, Paul SE, Karcher NR, Hansen I, Baranger DAA, Edwards A, Grotzinger A; Substance Use Disorder Working Group of the Psychiatric Genomics Consortium; Tucker-Drob EM, Kranzler HR, Davis LK, Sanchez-Roige S, Polimanti R, Gelernter J, Edenberg HJ, Bogdan R, Agrawal A. Hatoum AS, et al. Among authors: jennings mv. Nat Ment Health. 2023 Mar;1(3):210-223. doi: 10.1038/s44220-023-00034-y. Epub 2023 Mar 22. Nat Ment Health. 2023. PMID: 37250466 Free PMC article.
Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.
Kember RL, Vickers-Smith R, Zhou H, Xu H, Jennings M, Dao C, Davis L, Sanchez-Roige S, Justice AC, Gelernter J, Vujkovic M, Kranzler HR. Kember RL, et al. Am J Psychiatry. 2023 Aug 1;180(8):584-593. doi: 10.1176/appi.ajp.21090892. Epub 2023 Jun 7. Am J Psychiatry. 2023. PMID: 37282553 Free PMC article.
Genome-Wide Association Studies of Coffee Intake in UK/US Participants of European Ancestry Uncover Gene-Cohort Influences.
Thorpe HHA, Fontanillas P, Pham BK, Meredith JJ, Jennings MV, Courchesne-Krak NS, Vilar-Ribó L, Bianchi SB, Mutz J; 23andMe Research Team; Elson SL, Khokhar JY, Abdellaoui A, Davis LK, Palmer AA, Sanchez-Roige S. Thorpe HHA, et al. Among authors: jennings mv. medRxiv [Preprint]. 2023 Sep 11:2023.09.09.23295284. doi: 10.1101/2023.09.09.23295284. medRxiv. 2023. Update in: Neuropsychopharmacology. 2024 Sep;49(10):1609-1618. doi: 10.1038/s41386-024-01870-x PMID: 37745582 Free PMC article. Updated. Preprint.
A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals.
Jennings MV, Martínez-Magaña JJ, Courchesne-Krak NS, Cupertino RB, Vilar-Ribó L, Bianchi SB, Hatoum AS, Atkinson EG, Giusti-Rodriguez P, Montalvo-Ortiz JL, Gelernter J, Artigas MS; 23andMe, Inc. Research Team; Elson SL, Edenberg HJ, Fontanillas P, Palmer AA, Sanchez-Roige S. Jennings MV, et al. EBioMedicine. 2024 May;103:105086. doi: 10.1016/j.ebiom.2024.105086. Epub 2024 Apr 4. EBioMedicine. 2024. PMID: 38580523 Free PMC article.
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