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Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis.
Ishii T, Ruiz-Torruella M, Kim JY, Kanzaki H, Albassam A, Wisitrasameewong W, Shindo S, Pierrelus R, Heidari A, Kandalam U, Nakamura S, Movila A, Minond D, Kawai T. Ishii T, et al. Among authors: kanzaki h. J Cell Mol Med. 2023 Jun;27(12):1750-1756. doi: 10.1111/jcmm.17416. Epub 2023 May 11. J Cell Mol Med. 2023. PMID: 37170687 Free PMC article.
Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor.
Kanzaki H, Movila A, Kayal R, Napimoga MH, Egashira K, Dewhirst F, Sasaki H, Howait M, Al-Dharrab A, Mira A, Han X, Taubman MA, Nichols FC, Kawai T. Kanzaki H, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):452-462. doi: 10.1016/j.bbalip.2017.01.008. Epub 2017 Jan 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28153611 Free PMC article.
Activation of Nuclear Factor Erythroid 2-Related Factor 2 Transcriptionally Upregulates Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Expression and Inhibits Ectopic Calcification in Mice.
Tomomi I, Kanzaki H, Shimoyama M, Tohyama S, Ishikawa M, Katsumata Y, Arai C, Wada S, Manase S, Tomonari H. Tomomi I, et al. Among authors: kanzaki h. Antioxidants (Basel). 2024 Jul 24;13(8):896. doi: 10.3390/antiox13080896. Antioxidants (Basel). 2024. PMID: 39199142 Free PMC article.
RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice.
Kanzaki H, Shinohara F, Itohiya K, Yamaguchi Y, Katsumata Y, Matsuzawa M, Fukaya S, Miyamoto Y, Wada S, Nakamura Y. Kanzaki H, et al. FASEB J. 2017 Feb;31(2):781-792. doi: 10.1096/fj.201600826R. Epub 2016 Nov 11. FASEB J. 2017. PMID: 27836987
Bach1 nuclear export might be a therapeutic target for such bone destructive diseases as rheumatoid arthritis, osteoporosis, and periodontitis.-Kanzaki, H., Shinohara, F., Itohiya, K., Yamaguchi, Y., Katsumata, Y., Matsuzawa, M., Fukaya, S., Miyamoto, Y., Wada, S., …
Bach1 nuclear export might be a therapeutic target for such bone destructive diseases as rheumatoid arthritis, osteoporosis, and periodontit …
778 results