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Correction to "Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign".
Doering SR, Freeman K, Debevec G, Geer P, Santos RG, Lavoi TM, Giulianotti MA, Pinilla C, Appel JR, Houghten RA, Ericson MD, Haskell-Luevano C. Doering SR, et al. Among authors: ericson md. J Med Chem. 2023 May 25;66(10):7063-7065. doi: 10.1021/acs.jmedchem.3c00588. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155917 No abstract available.
Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.
Ericson MD, Lensing CJ, Fleming KA, Schlasner KN, Doering SR, Haskell-Luevano C. Ericson MD, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt A):2414-2435. doi: 10.1016/j.bbadis.2017.03.020. Epub 2017 Mar 29. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28363699 Free PMC article. Review.
Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor.
Ericson MD, Freeman KT, Schnell SM, Fleming KA, Haskell-Luevano C. Ericson MD, et al. J Med Chem. 2017 Oct 12;60(19):8103-8114. doi: 10.1021/acs.jmedchem.7b00856. Epub 2017 Oct 4. J Med Chem. 2017. PMID: 28813605 Free PMC article.
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in Mice.
Fleming KA, Ericson MD, Freeman KT, Adank DN, Lunzer MM, Wilber SL, Haskell-Luevano C. Fleming KA, et al. Among authors: ericson md. ACS Chem Neurosci. 2018 May 16;9(5):1141-1151. doi: 10.1021/acschemneuro.7b00495. Epub 2018 Feb 13. ACS Chem Neurosci. 2018. PMID: 29363944 Free PMC article.
Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors.
Ericson MD, Singh A, Tala SR, Haslach EM, Dirain MLS, Schaub JW, Flores V, Eick N, Lensing CJ, Freeman KT, Smeester BA, Adank DN, Wilber SL, Speth R, Haskell-Luevano C. Ericson MD, et al. J Med Chem. 2018 Apr 26;61(8):3738-3744. doi: 10.1021/acs.jmedchem.8b00251. Epub 2018 Apr 9. J Med Chem. 2018. PMID: 29578343 Free PMC article.
Arg-Phe-Phe d-Amino Acid Stereochemistry Scan in the Macrocyclic Agouti-Related Protein Antagonist Scaffold c[Pro-Arg-Phe-Phe-Xxx-Ala-Phe-DPro] Results in Unanticipated Melanocortin-1 Receptor Agonist Profiles.
Ericson MD, Koerperich ZM, Freeman KT, Fleming KA, Haskell-Luevano C. Ericson MD, et al. ACS Chem Neurosci. 2018 Dec 19;9(12):3015-3023. doi: 10.1021/acschemneuro.8b00218. Epub 2018 Jul 20. ACS Chem Neurosci. 2018. PMID: 29924583 Free PMC article.
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