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Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
Zhan W, Li D, Subramanyaswamy SB, Liu YJ, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H, Sherman J, Qin J, Herring M, Simwela NV, Waters AP, Sukenick G, Cui L, Rodriguez A, Deng H, Nathan CF, Kirkman LA, Lin G. Zhan W, et al. Cell Chem Biol. 2023 May 18;30(5):457-469.e11. doi: 10.1016/j.chembiol.2023.04.006. Epub 2023 May 5. Cell Chem Biol. 2023. PMID: 37148884 Free PMC article.
Structure of the human UBR5 E3 ubiquitin ligase.
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H. Wang F, et al. Among authors: zhan w. Structure. 2023 May 4;31(5):541-552.e4. doi: 10.1016/j.str.2023.03.010. Epub 2023 Apr 10. Structure. 2023. PMID: 37040767 Free PMC article.
Distinct myeloid-derived suppressor cell populations in human glioblastoma.
Jackson C, Cherry C, Bom S, Dykema AG, Wang R, Thompson E, Zhang M, Li R, Ji Z, Hou W, Zhan W, Zhang H, Choi J, Vaghasia A, Hansen L, Wang W, Bergsneider B, Jones KM, Rodriguez F, Weingart J, Lucas CH, Powell J, Elisseeff J, Yegnasubramanian S, Lim M, Bettegowda C, Ji H, Pardoll D. Jackson C, et al. Among authors: zhan w. Science. 2025 Jan 17;387(6731):eabm5214. doi: 10.1126/science.abm5214. Epub 2025 Jan 17. Science. 2025. PMID: 39818911
1,629 results