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Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
Chen Y, Lu W, Yang K, Duan X, Li M, Chen X, Zhang J, Kuang M, Liu S, Wu X, Zou G, Liu C, Hong C, He W, Liao J, Hou C, Zhang Z, Zheng Q, Chen J, Zhang N, Tang H, Vanderpool RR, Desai AA, Rischard F, Black SM, Garcia JGN, Makino A, Yuan JX, Zhong N, Wang J. Chen Y, et al. Among authors: tang h. Br J Pharmacol. 2020 Jun;177(12):2743-2764. doi: 10.1111/bph.15000. Epub 2020 Apr 27. Br J Pharmacol. 2020. PMID: 31976548 Free PMC article.
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats.
Zhang C, Lu W, Luo X, Liu S, Li Y, Zheng Q, Liu W, Wu X, Chen Y, Jiang Q, Zhang Z, Gu G, Chen J, Chen H, Liao J, Liu C, Hong C, Tang H, Sun D, Yang K, Wang J. Zhang C, et al. Among authors: tang h. Br J Pharmacol. 2021 Jan;178(1):217-235. doi: 10.1111/bph.15314. Epub 2020 Dec 14. Br J Pharmacol. 2021. PMID: 33140842 Free article.
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells.
Wang J, Liu W, Lu W, Luo X, Lin Y, Liu S, Qian J, Zhang C, Chen H, Li Y, Li X, Chen J, Chen Y, Jiang Q, Liu C, Hong C, Wang T, Tang H, Zhong N, Yang J, Yang K, Sun D. Wang J, et al. Among authors: tang h. Biochem Pharmacol. 2022 May;199:114986. doi: 10.1016/j.bcp.2022.114986. Epub 2022 Mar 8. Biochem Pharmacol. 2022. PMID: 35276216
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension.
Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, Wang Z, Zhang Q, Balistrieri A, Ayon RJ, Rischard F, Vanderpool R, Chen J, Zhou G, Desai AA, Black SM, Garcia JGN, Yuan JX, Makino A. Tang H, et al. JACC Basic Transl Sci. 2018 Dec 31;3(6):744-762. doi: 10.1016/j.jacbts.2018.08.009. eCollection 2018 Dec. JACC Basic Transl Sci. 2018. PMID: 30623134 Free PMC article.
A novel rat model of pulmonary hypertension induced by mono treatment with SU5416.
Chen Y, Kuang M, Liu S, Hou C, Duan X, Yang K, He W, Liao J, Zheng Q, Zou G, Chen H, Yan H, Chen J, Li Y, Zhou Y, Luo X, Jiang Q, Tang H, Lu W, Wang J. Chen Y, et al. Among authors: tang h. Hypertens Res. 2020 Aug;43(8):754-764. doi: 10.1038/s41440-020-0457-6. Epub 2020 May 29. Hypertens Res. 2020. PMID: 32472112
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