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The 'omics of obesity in B-cell acute lymphoblastic leukemia.
Geitgey DK, Lee M, Cottrill KA, Jaffe M, Pilcher W, Bhasin S, Randall J, Ross AJ, Salemi M, Castillo-Castrejon M, Kilgore MB, Brown AC, Boss JM, Johnston R, Fitzpatrick AM, Kemp ML, English R, Weaver E, Bagchi P, Walsh R, Scharer CD, Bhasin M, Chandler JD, Haynes KA, Wellberg EA, Henry CJ. Geitgey DK, et al. Among authors: scharer cd. J Natl Cancer Inst Monogr. 2023 May 4;2023(61):12-29. doi: 10.1093/jncimonographs/lgad014. J Natl Cancer Inst Monogr. 2023. PMID: 37139973 Free PMC article.
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine.
Meza-Perez S, Liu M, Silva-Sanchez A, Morrow CD, Eipers PG, Lefkowitz EJ, Ptacek T, Scharer CD, Rosenberg AF, Hill DD, Arend RC, Gray MJ, Randall TD. Meza-Perez S, et al. Among authors: scharer cd. Cell Host Microbe. 2024 Jul 10;32(7):1177-1191.e7. doi: 10.1016/j.chom.2024.06.003. Epub 2024 Jun 27. Cell Host Microbe. 2024. PMID: 38942027
Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.
McManus DT, Valanparambil RM, Medina CB, Hu Y, Scharer CD, Sobierajska E, Chang DY, Wieland A, Lee J, Nasti TH, Hashimoto M, Ross JL, Prokhnevska N, Cardenas MA, Gill AL, Clark EC, Abadie K, Kueh HY, Kaye J, Au-Yeung BB, Kissick HT, Ahmed R. McManus DT, et al. Among authors: scharer cd. Res Sq [Preprint]. 2024 Feb 12:rs.3.rs-3922168. doi: 10.21203/rs.3.rs-3922168/v1. Res Sq. 2024. Update in: Nature. 2025 Jan 8. doi: 10.1038/s41586-024-08562-y PMID: 38410458 Free PMC article. Updated. Preprint.
Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness.
Eggert J, Zinzow-Kramer WM, Hu Y, Tsai YL, Weiss A, Salaita K, Scharer CD, Au-Yeung BB. Eggert J, et al. Among authors: scharer cd. bioRxiv [Preprint]. 2023 Jan 28:2023.01.27.525946. doi: 10.1101/2023.01.27.525946. bioRxiv. 2023. Update in: Sci Signal. 2024 Feb 6;17(822):eadh0439. doi: 10.1126/scisignal.adh0439 PMID: 36747815 Free PMC article. Updated. Preprint.
Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.
Cooper L, Xu H, Polmear J, Kealy L, Szeto C, Pang ES, Gupta M, Kirn A, Taylor JJ, Jackson KJL, Broomfield BJ, Nguyen A, Gago da Graça C, La Gruta N, Utzschneider DT, Groom JR, Martelotto L, Parish IA, O'Keeffe M, Scharer CD, Gras S, Good-Jacobson KL. Cooper L, et al. Among authors: scharer cd. Immunity. 2024 May 14;57(5):1037-1055.e6. doi: 10.1016/j.immuni.2024.03.016. Epub 2024 Apr 8. Immunity. 2024. PMID: 38593796
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