Malacaria E - Search Results

1

Therapeutic disruption of RAD52-ssDNA complexation via novel drug-like inhibitors.

Bhat DS, Malacaria E, Biagi LD, Razzaghi M, Honda M, Hobbs KF, Hengel SR, Pichierri P, Spies MA, Spies M. Bhat DS, et al. Among authors: malacaria e. NAR Cancer. 2023 May 1;5(2):zcad018. doi: 10.1093/narcan/zcad018. eCollection 2023 Jun. NAR Cancer. 2023. PMID: 37139244 Free PMC article.

2

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.

Murfuni I, Basile G, Subramanyam S, Malacaria E, Bignami M, Spies M, Franchitto A, Pichierri P. Murfuni I, et al. Among authors: malacaria e. PLoS Genet. 2013 Oct;9(10):e1003910. doi: 10.1371/journal.pgen.1003910. Epub 2013 Oct 31. PLoS Genet. 2013. PMID: 24204313 Free PMC article.

3

Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells.

Hengel SR, Malacaria E, Folly da Silva Constantino L, Bain FE, Diaz A, Koch BG, Yu L, Wu M, Pichierri P, Spies MA, Spies M. Hengel SR, et al. Among authors: malacaria e. Elife. 2016 Jul 19;5:e14740. doi: 10.7554/eLife.14740. Elife. 2016. PMID: 27434671 Free PMC article.

4

SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

Malacaria E, Franchitto A, Pichierri P. Malacaria E, et al. Sci Rep. 2017 Mar 14;7:44464. doi: 10.1038/srep44464. Sci Rep. 2017. PMID: 28290553 Free PMC article.

5

Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.

Palma A, Pugliese GM, Murfuni I, Marabitti V, Malacaria E, Rinalducci S, Minoprio A, Sanchez M, Mazzei F, Zolla L, Franchitto A, Pichierri P. Palma A, et al. Among authors: malacaria e. Nucleic Acids Res. 2018 Jun 1;46(10):5109-5124. doi: 10.1093/nar/gky280. Nucleic Acids Res. 2018. PMID: 29850896 Free PMC article.

6

ATM pathway activation limits R-loop-associated genomic instability in Werner syndrome cells.

Marabitti V, Lillo G, Malacaria E, Palermo V, Sanchez M, Pichierri P, Franchitto A. Marabitti V, et al. Among authors: malacaria e. Nucleic Acids Res. 2019 Apr 23;47(7):3485-3502. doi: 10.1093/nar/gkz025. Nucleic Acids Res. 2019. PMID: 30657978 Free PMC article.

7

Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation.

Malacaria E, Pugliese GM, Honda M, Marabitti V, Aiello FA, Spies M, Franchitto A, Pichierri P. Malacaria E, et al. Nat Commun. 2019 Mar 29;10(1):1412. doi: 10.1038/s41467-019-09196-9. Nat Commun. 2019. PMID: 30926821 Free PMC article.

8

Author Correction: Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation.

Malacaria E, Pugliese GM, Honda M, Marabitti V, Aiello FA, Spies M, Franchitto A, Pichierri P. Malacaria E, et al. Nat Commun. 2019 May 1;10(1):2023. doi: 10.1038/s41467-019-10072-9. Nat Commun. 2019. PMID: 31043602 Free PMC article.

9

RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease.

Aiello FA, Palma A, Malacaria E, Zheng L, Campbell JL, Shen B, Franchitto A, Pichierri P. Aiello FA, et al. Among authors: malacaria e. Nucleic Acids Res. 2019 Jul 26;47(13):6796-6810. doi: 10.1093/nar/gkz431. Nucleic Acids Res. 2019. PMID: 31114910 Free PMC article.

10

Checkpoint Defects Elicit a WRNIP1-Mediated Response to Counteract R-Loop-Associated Genomic Instability.

Marabitti V, Lillo G, Malacaria E, Palermo V, Pichierri P, Franchitto A. Marabitti V, et al. Among authors: malacaria e. Cancers (Basel). 2020 Feb 7;12(2):389. doi: 10.3390/cancers12020389. Cancers (Basel). 2020. PMID: 32046194 Free PMC article.

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