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Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.
Wang M, Wisniewski CA, Xiong C, Chhoy P, Goel HL, Kumar A, Zhu LJ, Li R, St Louis PA, Ferreira LM, Pakula H, Xu Z, Loda M, Jiang Z, Brehm MA, Mercurio AM. Wang M, et al. Among authors: kumar a. Sci Transl Med. 2023 May 3;15(694):eade5855. doi: 10.1126/scitranslmed.ade5855. Epub 2023 May 3. Sci Transl Med. 2023. PMID: 37134151
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer.
Xu Z, Goel HL, Burkart C, Burman L, Chong YE, Barber AG, Geng Y, Zhai L, Wang M, Kumar A, Menefee A, Polizzi C, Eide L, Rauch K, Rahman J, Hamel K, Fogassy Z, Klopp-Savino S, Paz S, Zhang M, Cubitt A, Nangle LA, Mercurio AM. Xu Z, et al. Among authors: kumar a. Sci Transl Med. 2023 May 3;15(694):eadf1128. doi: 10.1126/scitranslmed.adf1128. Epub 2023 May 3. Sci Transl Med. 2023. PMID: 37134152 Free PMC article.
Engineered ipilimumab variants that bind human and mouse CTLA-4.
Robison B, Diong SJ, Kumar A, Moon TM, Chang O, Chau B, Bee C, Barman I, Rajpal A, Korman AJ, West S, Strop P, Lee PS. Robison B, et al. Among authors: kumar a. MAbs. 2025 Dec;17(1):2451296. doi: 10.1080/19420862.2025.2451296. Epub 2025 Jan 24. MAbs. 2025. PMID: 39849917
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