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334 results

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Page 1
Cardiovascular Disease Risk Assessment Using Traditional Risk Factors and Polygenic Risk Scores in the Million Veteran Program.
Vassy JL, Posner DC, Ho YL, Gagnon DR, Galloway A, Tanukonda V, Houghton SC, Madduri RK, McMahon BH, Tsao PS, Damrauer SM, O'Donnell CJ, Assimes TL, Casas JP, Gaziano JM, Pencina MJ, Sun YV, Cho K, Wilson PWF. Vassy JL, et al. Among authors: casas jp. JAMA Cardiol. 2023 Jun 1;8(6):564-574. doi: 10.1001/jamacardio.2023.0857. JAMA Cardiol. 2023. PMID: 37133828 Free PMC article.
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program.
Verma A, Tsao N, Thomann L, Ho YL, Iyengar S, Luoh SW, Carr R, Crawford D, Efird JT, Huffman J, Hung A, Ivey K, Levin M, Lynch J, Natarajan P, Pyarajan S, Bick A, Costa L, Genovese G, Hauger R, Madduri R, Pathak G, Polimanti R, Voight B, Vujkovic M, Zekavat M, Zhao H, Ritchie MD; VA Million Veteran Program COVID-19 Science Initiative; Chang KM, Cho K, Casas JP, Tsao PS, Gaziano JM, O'Donnell C, Damrauer S, Liao K. Verma A, et al. Among authors: casas jp. medRxiv [Preprint]. 2021 Oct 15:2021.05.18.21257396. doi: 10.1101/2021.05.18.21257396. medRxiv. 2021. Update in: PLoS Genet. 2022 Apr 28;18(4):e1010113. doi: 10.1371/journal.pgen.1010113 PMID: 34642702 Free PMC article. Updated. Preprint.
Fibromuscular Dysplasia and Abdominal Aortic Aneurysms Are Dimorphic Sex-Specific Diseases With Shared Complex Genetic Architecture.
Katz AE, Yang ML, Levin MG, Tcheandjieu C, Mathis M, Hunker K, Blackburn S, Eliason JL, Coleman DM, Fendrikova-Mahlay N, Gornik HL, Karmakar M, Hill H, Xu C, Zawistowski M, Brummett CM, Zoellner S, Zhou X, O'Donnell CJ, Douglas JA, Assimes TL, Tsao PS; VA Million Veteran Program; Li JZ, Damrauer SM, Stanley JC, Ganesh SK. Katz AE, et al. Circ Genom Precis Med. 2022 Dec;15(6):e003496. doi: 10.1161/CIRCGEN.121.003496. Epub 2022 Nov 14. Circ Genom Precis Med. 2022. PMID: 36374587 Free PMC article.
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Ruderfer DM, Harvey PD, McMahon BH, Oslin DW, Beckham JC, Hauser ER, Hauser MA; Million Veteran Program Suicide Exemplar Workgroup, the International Suicide Genetics Consortium, the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and the Veterans Affairs Million Veteran Program. Kimbrel NA, et al. JAMA Psychiatry. 2023 Feb 1;80(2):135-145. doi: 10.1001/jamapsychiatry.2022.3896. JAMA Psychiatry. 2023. PMID: 36515925 Free PMC article.
Genetic architecture of heart failure with preserved versus reduced ejection fraction.
Joseph J, Liu C, Hui Q, Aragam K, Wang Z, Charest B, Huffman JE, Keaton JM, Edwards TL, Demissie S, Djousse L, Casas JP, Gaziano JM, Cho K, Wilson PWF, Phillips LS; VA Million Veteran Program; O'Donnell CJ, Sun YV. Joseph J, et al. Among authors: casas jp. Nat Commun. 2022 Dec 14;13(1):7753. doi: 10.1038/s41467-022-35323-0. Nat Commun. 2022. PMID: 36517512 Free PMC article.
Comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans.
Dickerman BA, Gerlovin H, Madenci AL, Figueroa Muñiz MJ, Wise JK, Adhikari N, Ferolito BR, Kurgansky KE, Gagnon DR, Cho K, Casas JP, Hernán MA. Dickerman BA, et al. Among authors: casas jp. Nat Microbiol. 2023 Jan;8(1):55-63. doi: 10.1038/s41564-022-01272-z. Epub 2023 Jan 2. Nat Microbiol. 2023. PMID: 36593297 Free PMC article.
Framework of the Centralized Interactive Phenomics Resource (CIPHER) standard for electronic health data-based phenomics knowledgebase.
Honerlaw J, Ho YL, Fontin F, Gosian J, Maripuri M, Murray M, Sangar R, Galloway A, Zimolzak AJ, Whitbourne SB, Casas JP, Ramoni RB, Gagnon DR, Cai T, Liao KP, Gaziano JM, Muralidhar S, Cho K. Honerlaw J, et al. Among authors: casas jp. J Am Med Inform Assoc. 2023 Apr 19;30(5):958-964. doi: 10.1093/jamia/ocad030. J Am Med Inform Assoc. 2023. PMID: 36882092 Free PMC article.
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Sun YV, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao PS, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano MJ, Madduri RK, Damrauer SM, Liao KP. Verma A, et al. Among authors: casas jp. medRxiv [Preprint]. 2023 Jun 29:2023.06.28.23291975. doi: 10.1101/2023.06.28.23291975. medRxiv. 2023. Update in: Science. 2024 Jul 19;385(6706):eadj1182. doi: 10.1126/science.adj1182 PMID: 37425708 Free PMC article. Updated. Preprint.
Comparison of the Test-negative Design and Cohort Design With Explicit Target Trial Emulation for Evaluating COVID-19 Vaccine Effectiveness.
Li G, Gerlovin H, Figueroa Muñiz MJ, Wise JK, Madenci AL, Robins JM, Aslan M, Cho K, Gaziano JM, Lipsitch M, Casas JP, Hernán MA, Dickerman BA. Li G, et al. Among authors: casas jp. Epidemiology. 2024 Mar 1;35(2):137-149. doi: 10.1097/EDE.0000000000001709. Epub 2023 Dec 18. Epidemiology. 2024. PMID: 38109485 Clinical Trial.
Protein identification for stroke progression via Mendelian Randomization in Million Veteran Program and UK Biobank.
Elmore A, Adhikari N, Hartley AE, Javier Aparicio H, Posner DC, Hemani G, Tilling K, Gaunt TR, Wilson P, Casas JP, Michael Gaziano J, Smith GD, Paternoster L, Cho K, Peloso GM. Elmore A, et al. Among authors: casas jp. medRxiv [Preprint]. 2024 Feb 1:2024.01.31.24302111. doi: 10.1101/2024.01.31.24302111. medRxiv. 2024. Update in: Stroke. 2024 Aug;55(8):2045-2054. doi: 10.1161/STROKEAHA.124.047103 PMID: 38352469 Free PMC article. Updated. Preprint.
334 results