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In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1 -mutant lung cancer.
Deng J, Peng DH, Fenyo D, Yuan H, Lopez A, Levin DS, Meynardie M, Quinteros M, Ranieri M, Sahu S, Lau SCM, Shum E, Velcheti V, Punekar SR, Rekhtman N, Dowling CM, Weerasekara V, Xue Y, Ji H, Siu Y, Jones D, Hata AN, Shimamura T, Poirier JT, Rudin CM, Hattori T, Koide S, Papagiannakopoulos T, Neel BG, Bardeesy N, Wong KK. Deng J, et al. Among authors: jones d. bioRxiv [Preprint]. 2023 Apr 20:2023.04.18.537350. doi: 10.1101/2023.04.18.537350. bioRxiv. 2023. PMID: 37131623 Free PMC article. Preprint.
Unraveling cysteine deficiency-associated rapid weight loss.
Varghese A, Gusarov I, Gamallo-Lana B, Dolgonos D, Mankan Y, Shamovsky I, Phan M, Jones R, Gomez-Jenkins M, White E, Wang R, Jones D, Papagiannakopoulos T, Pacold ME, Mar AC, Littman DR, Nudler E. Varghese A, et al. Among authors: jones r, jones d. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605703. doi: 10.1101/2024.07.30.605703. bioRxiv. 2024. PMID: 39131293 Free PMC article. Preprint.
Microbiota and metabolic adaptation shape Staphylococcus aureus virulence and antimicrobial resistance during intestinal colonization.
Zhou C, Pawline MB, Pironti A, Morales SM, Perault AI, Ulrich RJ, Podkowik M, Lejeune A, DuMont A, Stubbe FX, Korman A, Jones DR, Schluter J, Richardson AR, Fey PD, Drlica K, Cadwell K, Torres VJ, Shopsin B. Zhou C, et al. Among authors: jones dr. bioRxiv [Preprint]. 2024 May 11:2024.05.11.593044. doi: 10.1101/2024.05.11.593044. bioRxiv. 2024. PMID: 38766195 Free PMC article. Preprint.
DELE1 promotes translation-associated homeostasis, growth, and survival in mitochondrial myopathy.
Lin HP, Petersen JD, Gilsrud AJ, Madruga A, D'Silva TM, Huang X, Shammas MK, Randolph NP, Li Y, Jones DR, Pacold ME, Narendra DP. Lin HP, et al. Among authors: d silva tm, jones dr. bioRxiv [Preprint]. 2024 Feb 29:2024.02.29.582673. doi: 10.1101/2024.02.29.582673. bioRxiv. 2024. Update in: EMBO J. 2024 Nov;43(22):5548-5585. doi: 10.1038/s44318-024-00242-x PMID: 38529505 Free PMC article. Updated. Preprint.
Tofacitinib uptake by patient-derived intestinal organoids predicts individual clinical responsiveness.
Jang KK, Ercelen D, Cen Feng JYC, Gurunathan S, Zhou C, Korman A, Newell L, Hudesman D, Jones DR, Loke P, Axelrad JE, Cadwell K. Jang KK, et al. Among authors: jones dr. bioRxiv [Preprint]. 2024 Mar 6:2024.03.02.583137. doi: 10.1101/2024.03.02.583137. bioRxiv. 2024. Update in: Gastroenterology. 2024 Dec;167(7):1453-1456.e5. doi: 10.1053/j.gastro.2024.07.035 PMID: 38712048 Free PMC article. Updated. Preprint.
Patient Subtyping Analysis of Baseline Multi-omic Data Reveals Distinct Pre-immune States Predictive of Vaccination Responses.
Bayrak CS, Forst C, Jones DR, Gresham D, Pushalkar S, Wu S, Vogel C, Mahal L, Ghedin E, Ross T, García-Sastre A, Zhang B. Bayrak CS, et al. Among authors: jones dr. bioRxiv [Preprint]. 2024 Jan 22:2024.01.18.576213. doi: 10.1101/2024.01.18.576213. bioRxiv. 2024. Update in: Clin Immunol. 2024 Sep;266:110333. doi: 10.1016/j.clim.2024.110333 PMID: 38328256 Free PMC article. Updated. Preprint.
Longitudinal FDG-PET Metabolic Change Along the Lewy Body Continuum.
Ferreira D, Przybelski SA, Lesnick TG, Diaz-Galvan P, Schwarz CG, Murray MM, Dickson DW, Nguyen A, Reichard RR, Senjem ML, Gunter JL, Jack CR Jr, Min PH, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones DT, Botha H, St Louis EK, Knopman DS, Graff-Radford NR, Day GS, Ferman TJ, Kremers WK, Petersen RC, Boeve BF, Lowe VJ, Kantarci K. Ferreira D, et al. Among authors: jones dt. JAMA Neurol. 2025 Jan 13. doi: 10.1001/jamaneurol.2024.4643. Online ahead of print. JAMA Neurol. 2025. PMID: 39804619
Severity of Impaired Oxygenation and Conservative Oxygenation Targets in Mechanically Ventilated Children: A Post Hoc Subgroup Analysis of the Oxy-PICU Trial of Conservative Oxygenation.
Ray S, Wiegand M, Gould DW, Harrison DA, Mouncey PR, Peters MJ; Oxy-PICU Investigators of the United Kingdom Paediatric Critical Care Society Study Group. Ray S, et al. Pediatr Crit Care Med. 2025 Jan 13. doi: 10.1097/PCC.0000000000003686. Online ahead of print. Pediatr Crit Care Med. 2025. PMID: 39803991
Comparative genomic analysis of Fusarium oxysporum f. sp. lycopersici reveals telomeric duplications of a lineage-specific region carrying SIX8 and PSL1 and genome-wide expansion of Foxy transposable elements.
Sun X, Wang Y, Wang J, Liu Y, Song D, Fu J, Jones D, Wang D, Liu M, Ma L. Sun X, et al. Among authors: jones d. Int J Biol Macromol. 2025 Jan 10:139636. doi: 10.1016/j.ijbiomac.2025.139636. Online ahead of print. Int J Biol Macromol. 2025. PMID: 39800020
A novel interleukin-10 antibody graft to treat inflammatory bowel disease.
DiDonato M, Simpson CT, Vo T, Knuth M, Geierstanger B, Jamontt J, Jones DH, Fathman JW, DeLarosa D, Junt T, Picard D, Sommer U, Bagger M, Peters E, Meeusen S, Spraggon G. DiDonato M, et al. Among authors: jones dh. Structure. 2025 Jan 9:S0969-2126(24)00545-8. doi: 10.1016/j.str.2024.12.010. Online ahead of print. Structure. 2025. PMID: 39798572
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