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Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction.
Selli ME, Landmann JH, Terekhova M, Lattin J, Heard A, Hsu YS, Chang TC, Chang J, Warrington J, Ha H, Kingston N, Hogg G, Slade M, Berrien-Elliott MM, Foster M, Kersting-Schadek S, Gruszczynska A, DeNardo D, Fehniger TA, Artyomov M, Singh N. Selli ME, et al. Among authors: hsu ys. Blood. 2023 Jun 29;141(26):3153-3165. doi: 10.1182/blood.2023020100. Blood. 2023. PMID: 37130030 Free PMC article.
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.
Heard A, Landmann JH, Hansen AR, Papadopolou A, Hsu YS, Selli ME, Warrington JM, Lattin J, Chang J, Ha H, Haug-Kroeper M, Doray B, Gill S, Ruella M, Hayer KE, Weitzman MD, Green AM, Fluhrer R, Singh N. Heard A, et al. Among authors: hsu ys. Nat Commun. 2022 Jun 11;13(1):3367. doi: 10.1038/s41467-022-31035-7. Nat Commun. 2022. PMID: 35690611 Free PMC article.
Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity.
Yi J, Miller AT, Archambault AS, Jones AJ, Bradstreet TR, Bandla S, Hsu YS, Edelson BT, Zhou YW, Fremont DH, Egawa T, Singh N, Wu GF, Hsieh CS. Yi J, et al. Among authors: hsu ys. Sci Immunol. 2022 Oct 14;7(76):eabo0777. doi: 10.1126/sciimmunol.abo0777. Epub 2022 Oct 7. Sci Immunol. 2022. PMID: 36206355 Free PMC article.
Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction.
Selli ME, Landmann JH, Terekhova M, Lattin J, Heard A, Hsu YS, Chang TC, Chang J, Warrington J, Ha H, Kingston N, Hogg G, Slade M, Berrien-Elliot MM, Foster M, Kersting-Schadek S, Gruszczynska A, DeNardo D, Fehniger TA, Artyomov M, Singh N. Selli ME, et al. Among authors: hsu ys. bioRxiv [Preprint]. 2023 Jan 27:2023.01.26.525725. doi: 10.1101/2023.01.26.525725. bioRxiv. 2023. Update in: Blood. 2023 Jun 29;141(26):3153-3165. doi: 10.1182/blood.2023020100 PMID: 36747791 Free PMC article. Updated. Preprint.
Rational Protein Engineering to Enhance MHC-Independent T-cell Receptors.
Chang JF, Landmann JH, Chang TC, Selli ME, Tenzin Y, Warrington JM, Ritchey J, Hsu YS, Slade M, Gupta DK, DiPersio JF, Holehouse AS, Singh N. Chang JF, et al. Among authors: hsu ys. Cancer Discov. 2024 Nov 1;14(11):2109-2121. doi: 10.1158/2159-8290.CD-23-1393. Cancer Discov. 2024. PMID: 38980802
Safety, tolerability, and efficacy of intranasally-administered detoxified LTh(αK) in mild-to-moderate COVID-19 patients: A randomized, double-blinded, placebo-controlled phase 2 study.
Cheng CY, Su YS, Chen CL, Chang M, Huang SW, Huang PN, Shih SR, Hsu YS, Chiu CH. Cheng CY, et al. Among authors: hsu ys. Hum Vaccin Immunother. 2024 Dec 31;20(1):2432105. doi: 10.1080/21645515.2024.2432105. Epub 2024 Nov 29. Hum Vaccin Immunother. 2024. PMID: 39611611 Free PMC article. Clinical Trial.
173 results