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Page 1
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.
Weinstock JS, Laurie CA, Broome JG, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC, Chami N, Kenny EE, Loos RJF, Fornage M, Redline S, Cade BE, Gilliland FD, Chen Z, Gauderman WJ, Kumar R, Grammer L, Schleimer RP, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Qiao D, Weiss ST, Lasky-Su J, DeMeo DL, Palmer ND, Freedman BI, Bowden DW, Cho MH, Vasan RS, Johnson AD, Yanek LR, Becker LC, Kardia S, He J, Kaplan R, Heckbert SR, Smith NL, Wiggins KL, Arnett DK, Irvin MR, Tiwari H, Correa A, Raffield LM, Gao Y, de Andrade M, Rotter JI, Rich SS, Manichaikul AW, Konkle BA, Johnsen JM, Wheeler MM, Custer BS, Duggirala R, Curran JE, Blangero J, Gui H, Xiao S, Williams LK, Meyers DA, Li X, Ortega V, McGarvey S, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Darbar D, Roden D, Albert C, Kooperberg C, Desai P, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Mathias R, Natarajan P, Jaiswal S, Reiner AP, Bick AG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Weinstock JS, et al. Among authors: grammer l. Sci Adv. 2023 Apr 28;9(17):eabm4945. doi: 10.1126/sciadv.abm4945. Epub 2023 Apr 26. Sci Adv. 2023. PMID: 37126548 Free PMC article.
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.
Kessler MD, Yerges-Armstrong L, Taub MA, Shetty AC, Maloney K, Jeng LJB, Ruczinski I, Levin AM, Williams LK, Beaty TH, Mathias RA, Barnes KC; Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA); O'Connor TD. Kessler MD, et al. Nat Commun. 2016 Oct 11;7:12521. doi: 10.1038/ncomms12521. Nat Commun. 2016. PMID: 27725664 Free PMC article.
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.
Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, Levin AM, Song W, Torres R, Padhukasahasram B, Eng C, Mejia-Mejia DA, Ferguson T, Qin ZS, Scott AF, Yazdanbakhsh M, Wilson JG, Marrugo J, Lange LA, Kumar R, Avila PC, Williams LK, Watson H, Ware LB, Olopade C, Olopade O, Oliveira R, Ober C, Nicolae DL, Meyers D, Mayorga A, Knight-Madden J, Hartert T, Hansel NN, Foreman MG, Ford JG, Faruque MU, Dunston GM, Caraballo L, Burchard EG, Bleecker E, Araujo MI, Herrera-Paz EF, Gietzen K, Grus WE, Bamshad M, Bustamante CD, Kenny EE, Hernandez RD, Beaty TH, Ruczinski I, Akey J; CAAPA; Barnes KC. Mathias RA, et al. Nat Commun. 2016 Oct 11;7:12522. doi: 10.1038/ncomms12522. Nat Commun. 2016. PMID: 27725671 Free PMC article.
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC; CAAPA. Daya M, et al. Nat Commun. 2019 Feb 20;10(1):880. doi: 10.1038/s41467-019-08469-7. Nat Commun. 2019. PMID: 30787307 Free PMC article.
Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC; CAAPA. Daya M, et al. Nat Commun. 2019 Sep 4;10(1):4082. doi: 10.1038/s41467-019-12158-w. Nat Commun. 2019. PMID: 31484942 Free PMC article.
Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis.
Iwasaki N, Poposki JA, Kidoguchi M, Oka A, Klingler AI, Stevens WW, Suh LA, Bai J, Peters AT, Grammer LC, Welch KC, Smith SS, Conley DB, Bochner BS, Schleimer RP, Kern RC, Tan BK, Kato A. Iwasaki N, et al. Among authors: grammer lc. J Allergy Clin Immunol. 2024 Nov 9:S0091-6749(24)01176-X. doi: 10.1016/j.jaci.2024.10.032. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39522652
Single cell RNA sequencing of human eosinophils from nasal polyps reveals eosinophil heterogeneity in chronic rhinosinusitis tissue.
Iwasaki N, Poposki JA, Oka A, Kidoguchi M, Klingler AI, Suh LA, Bai J, Stevens WW, Peters AT, Grammer LC, Welch KC, Smith SS, Conley DB, Schleimer RP, Kern RC, Bochner BS, Tan BK, Kato A. Iwasaki N, et al. Among authors: grammer lc. J Allergy Clin Immunol. 2024 Oct;154(4):952-964. doi: 10.1016/j.jaci.2024.05.014. Epub 2024 May 24. J Allergy Clin Immunol. 2024. PMID: 38797240
Associations Between Chronic Rhinosinusitis and the Development of Non-Cystic Fibrosis Bronchiectasis.
Kim SL, Schwartz BS, Vu TH, Conley DB, Grammer LC, Guo A, Kato A, Kern RC, Prickett MH, Schleimer RP, Smith S, Stevens WW, Suh L, Tan BK, Welch KC, Peters AT. Kim SL, et al. Among authors: grammer lc. J Allergy Clin Immunol Pract. 2024 Nov;12(11):3116-3122.e2. doi: 10.1016/j.jaip.2024.07.027. Epub 2024 Aug 5. J Allergy Clin Immunol Pract. 2024. PMID: 39111364
5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function.
Walker MT, Bloodworth JC, Kountz TS, McCarty SL, Green JE, Ferrie RP, Campbell JA, Averill SH, Beckman KB, Grammer LC, Eng C, Avila PC, Farber HJ, Rodriguez-Cintron W, Rodriguez-Santana JR, Serebrisky D, Thyne SM, Seibold MA, Burchard EG, Kumar R, Cook-Mills JM. Walker MT, et al. Among authors: grammer lc. Front Allergy. 2024 May 23;5:1385168. doi: 10.3389/falgy.2024.1385168. eCollection 2024. Front Allergy. 2024. PMID: 38845678 Free PMC article.
330 results