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124 results

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A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variants.
Yang ML, Yuan TZ, Chan KY, Ding L, Han Z, Franco H, Holliday C, Kannan S, Davidson E, Doranz BJ, Chandran K, Miller EH, Plante JA, Weaver SC, Cho E, Kailasan S, Marsalek L, Giang H, Abdiche Y, Sato AK. Yang ML, et al. Among authors: doranz bj. Antib Ther. 2024 May 3;7(2):164-176. doi: 10.1093/abt/tbae009. eCollection 2024 Apr. Antib Ther. 2024. PMID: 38933534 Free PMC article.
Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
Wolters RM, Ferguson JA, Nuñez IA, Chen EE, Sornberger T, Myers L, Oeverdieck S, Raghavan SSR, Kona C, Handal LS, Esilu TE, Davidson E, Doranz BJ, Engdahl TB, Kose N, Williamson LE, Creech CB, Gibson-Corley KN, Ward AB, Crowe JE Jr. Wolters RM, et al. Among authors: doranz bj. Immunity. 2024 Jun 11;57(6):1413-1427.e9. doi: 10.1016/j.immuni.2024.05.002. Epub 2024 May 31. Immunity. 2024. PMID: 38823390
Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques.
Sankhala RS, Lal KG, Jensen JL, Dussupt V, Mendez-Rivera L, Bai H, Wieczorek L, Mayer SV, Zemil M, Wagner DA, Townsley SM, Hajduczki A, Chang WC, Chen WH, Donofrio GC, Jian N, King HAD, Lorang CG, Martinez EJ, Rees PA, Peterson CE, Schmidt F, Hart TJ, Duso DK, Kummer LW, Casey SP, Williams JK, Kannan S, Slike BM, Smith L, Swafford I, Thomas PV, Tran U, Currier JR, Bolton DL, Davidson E, Doranz BJ, Hatziioannou T, Bieniasz PD, Paquin-Proulx D, Reiley WW, Rolland M, Sullivan NJ, Vasan S, Collins ND, Modjarrad K, Gromowski GD, Polonis VR, Michael NL, Krebs SJ, Joyce MG. Sankhala RS, et al. Among authors: doranz bj. Nat Commun. 2024 Jan 3;15(1):200. doi: 10.1038/s41467-023-44265-0. Nat Commun. 2024. PMID: 38172512 Free PMC article.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Duran V, Rebellon-Sanchez DE, Sanz AM, Rosso F, Doranz BJ, Einav S, Matsen Iv FA, Goo L. Lubow J, et al. Among authors: doranz bj. PLoS Pathog. 2023 Oct 9;19(10):e1011722. doi: 10.1371/journal.ppat.1011722. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37812640 Free PMC article.
Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Sankhala RS, Dussupt V, Donofrio G, Gromowski GD, De La Barrera RA, Larocca RA, Mendez-Rivera L, Lee A, Choe M, Zaky W, Mantus G, Jensen JL, Chen WH, Gohain N, Bai H, McCracken MK, Mason RD, Leggat D, Slike BM, Tran U, Jian N, Abbink P, Peterson R, Mendes EA, Freitas de Oliveira Franca R, Calvet GA, Bispo de Filippis AM, McDermott A, Roederer M, Hernandez M, Albertus A, Davidson E, Doranz BJ, Rolland M, Robb ML, Lynch RM, Barouch DH, Jarman RG, Thomas SJ, Modjarrad K, Michael NL, Krebs SJ, Joyce MG. Sankhala RS, et al. Among authors: doranz bj. Cell Rep. 2023 Aug 29;42(8):112942. doi: 10.1016/j.celrep.2023.112942. Epub 2023 Aug 9. Cell Rep. 2023. PMID: 37561630 Free PMC article.
Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.
Jensen JL, Sankhala RS, Dussupt V, Bai H, Hajduczki A, Lal KG, Chang WC, Martinez EJ, Peterson CE, Golub ES, Rees PA, Mendez-Rivera L, Zemil M, Kavusak E, Mayer SV, Wieczorek L, Kannan S, Doranz BJ, Davidson E, Yang ES, Zhang Y, Chen M, Choe M, Wang L, Gromowski GD, Koup RA, Michael NL, Polonis VR, Rolland M, Modjarrad K, Krebs SJ, Joyce MG. Jensen JL, et al. Among authors: doranz bj. J Virol. 2023 Jul 27;97(7):e0159622. doi: 10.1128/jvi.01596-22. Epub 2023 Jul 3. J Virol. 2023. PMID: 37395646 Free PMC article.
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: doranz bj. Cell Host Microbe. 2023 Jun 14;31(6):1071-1072. doi: 10.1016/j.chom.2023.05.016. Cell Host Microbe. 2023. PMID: 37321165 Free PMC article. No abstract available.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Doranz BJ, Duran V, Sanchez DE, Sanz AM, Rosso F, Einav S, Matsen FA, Goo L. Lubow J, et al. Among authors: doranz bj. bioRxiv [Preprint]. 2023 Apr 10:2023.04.09.536175. doi: 10.1101/2023.04.09.536175. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Oct 9;19(10):e1011722. doi: 10.1371/journal.ppat.1011722 PMID: 37090561 Free PMC article. Updated. Preprint.
124 results