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NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, Huerta-Uribe A, Zatyka M, Silva LFSE, Torresi J, Zhang S, Hughes GW, Ward C, Kuechler ER, Cartwright D, Trushin S, Trushina E, Sahay G, Buganim Y, Lavery GG, Gsponer J, Anderson DG, Frickel EM, Rosenstock TR, Barrett T, Maddocks ODK, Tennant DA, Wang H, Jaenisch R, Korolchuk VI, Sarkar S. Sun C, et al. Among authors: sarkar s. Cell Rep. 2023 May 30;42(5):112372. doi: 10.1016/j.celrep.2023.112372. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086404 Free PMC article.
Mammalian macroautophagy at a glance.
Ravikumar B, Futter M, Jahreiss L, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Narayanan U, Renna M, Jimenez-Sanchez M, Sarkar S, Underwood B, Winslow A, Rubinsztein DC. Ravikumar B, et al. Among authors: sarkar s. J Cell Sci. 2009 Jun 1;122(Pt 11):1707-11. doi: 10.1242/jcs.031773. J Cell Sci. 2009. PMID: 19461070 Free PMC article. Review. No abstract available.
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
Underwood BR, Imarisio S, Fleming A, Rose C, Krishna G, Heard P, Quick M, Korolchuk VI, Renna M, Sarkar S, García-Arencibia M, O'Kane CJ, Murphy MP, Rubinsztein DC. Underwood BR, et al. Among authors: sarkar s. Hum Mol Genet. 2010 Sep 1;19(17):3413-29. doi: 10.1093/hmg/ddq253. Epub 2010 Jun 21. Hum Mol Genet. 2010. PMID: 20566712 Free PMC article.
Impaired autophagy in Lafora disease.
Knecht E, Aguado C, Sarkar S, Korolchuk VI, Criado-García O, Vernia S, Boya P, Sanz P, Rodríguez de Córdoba S, Rubinsztein DC. Knecht E, et al. Among authors: sarkar s. Autophagy. 2010 Oct;6(7):991-3. doi: 10.4161/auto6.7.13308. Epub 2010 Oct 11. Autophagy. 2010. PMID: 20818165 Free PMC article.
Lysosomal positioning coordinates cellular nutrient responses.
Korolchuk VI, Saiki S, Lichtenberg M, Siddiqi FH, Roberts EA, Imarisio S, Jahreiss L, Sarkar S, Futter M, Menzies FM, O'Kane CJ, Deretic V, Rubinsztein DC. Korolchuk VI, et al. Among authors: sarkar s. Nat Cell Biol. 2011 Apr;13(4):453-60. doi: 10.1038/ncb2204. Epub 2011 Mar 13. Nat Cell Biol. 2011. PMID: 21394080 Free PMC article.
Complex inhibitory effects of nitric oxide on autophagy.
Sarkar S, Korolchuk VI, Renna M, Imarisio S, Fleming A, Williams A, Garcia-Arencibia M, Rose C, Luo S, Underwood BR, Kroemer G, O'Kane CJ, Rubinsztein DC. Sarkar S, et al. Mol Cell. 2011 Jul 8;43(1):19-32. doi: 10.1016/j.molcel.2011.04.029. Mol Cell. 2011. PMID: 21726807 Free PMC article.
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling.
Sahay G, Querbes W, Alabi C, Eltoukhy A, Sarkar S, Zurenko C, Karagiannis E, Love K, Chen D, Zoncu R, Buganim Y, Schroeder A, Langer R, Anderson DG. Sahay G, et al. Among authors: sarkar s. Nat Biotechnol. 2013 Jul;31(7):653-8. doi: 10.1038/nbt.2614. Epub 2013 Jun 23. Nat Biotechnol. 2013. PMID: 23792629 Free PMC article.
Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease.
Sarkar S, Carroll B, Buganim Y, Maetzel D, Ng AH, Cassady JP, Cohen MA, Chakraborty S, Wang H, Spooner E, Ploegh H, Gsponer J, Korolchuk VI, Jaenisch R. Sarkar S, et al. Cell Rep. 2013 Dec 12;5(5):1302-15. doi: 10.1016/j.celrep.2013.10.042. Epub 2013 Nov 27. Cell Rep. 2013. PMID: 24290752 Free PMC article.
6,439 results