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Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness.
Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel AR, Simon MC, Karin M. Gu L, et al. Among authors: cunha e rocha k. Cell Metab. 2023 Jun 6;35(6):1009-1021.e9. doi: 10.1016/j.cmet.2023.03.021. Epub 2023 Apr 20. Cell Metab. 2023. PMID: 37084733 Free PMC article.
Host metabolic inflammation fueled by bacterial DNA.
Wang K, Cunha E Rocha K, Qin H, Zeng Z, Ying W. Wang K, et al. Among authors: cunha e rocha k. Trends Endocrinol Metab. 2024 Nov 27:S1043-2760(24)00294-7. doi: 10.1016/j.tem.2024.11.003. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 39609222 Review.
Author Correction: Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization.
Rohm TV, Castellani Gomes Dos Reis F, Isaac R, Murphy C, Cunha E Rocha K, Bandyopadhyay G, Gao H, Libster AM, Zapata RC, Lee YS, Ying W, Miciano C, Wang A, Olefsky JM. Rohm TV, et al. Among authors: cunha e rocha k. Nat Metab. 2024 Aug;6(8):1646. doi: 10.1038/s42255-024-01094-9. Nat Metab. 2024. PMID: 38969830 No abstract available.
Exosome-Mediated Impact on Systemic Metabolism.
Cunha E Rocha K, Ying W, Olefsky JM. Cunha E Rocha K, et al. Annu Rev Physiol. 2024 Feb 12;86:225-253. doi: 10.1146/annurev-physiol-042222-024535. Annu Rev Physiol. 2024. PMID: 38345906 Free article. Review.