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TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.
Park MD, Reyes-Torres I, LeBerichel J, Hamon P, LaMarche NM, Hegde S, Belabed M, Troncoso L, Grout JA, Magen A, Humblin E, Nair A, Molgora M, Hou J, Newman JH, Farkas AM, Leader AM, Dawson T, D'Souza D, Hamel S, Sanchez-Paulete AR, Maier B, Bhardwaj N, Martin JC, Kamphorst AO, Kenigsberg E, Casanova-Acebes M, Horowitz A, Brown BD, De Andrade LF, Colonna M, Marron TU, Merad M. Park MD, et al. Among authors: farkas am. Nat Immunol. 2023 May;24(5):792-801. doi: 10.1038/s41590-023-01475-4. Epub 2023 Apr 20. Nat Immunol. 2023. PMID: 37081148 Free PMC article.
Fibroblast Growth Factor Receptor 3 Alterations and Response to PD-1/PD-L1 Blockade in Patients with Metastatic Urothelial Cancer.
Wang L, Gong Y, Saci A, Szabo PM, Martini A, Necchi A, Siefker-Radtke A, Pal S, Plimack ER, Sfakianos JP, Bhardwaj N, Horowitz A, Farkas AM, Mulholland D, Fischer BS, Oh WK, Sharma P, Zhu J, Galsky MD. Wang L, et al. Among authors: farkas am. Eur Urol. 2019 Nov;76(5):599-603. doi: 10.1016/j.eururo.2019.06.025. Epub 2019 Jul 1. Eur Urol. 2019. PMID: 31272788 Free PMC article.
Harnessing Natural Killer Cell Function for Genitourinary Cancers.
Bhardwaj N, Farkas AM, Gul Z, Sfakianos JP. Bhardwaj N, et al. Among authors: farkas am. Urol Clin North Am. 2020 Nov;47(4):433-442. doi: 10.1016/j.ucl.2020.07.002. Epub 2020 Sep 2. Urol Clin North Am. 2020. PMID: 33008494 Free PMC article. Review.
Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing.
Wang L, Sfakianos JP, Beaumont KG, Akturk G, Horowitz A, Sebra RP, Farkas AM, Gnjatic S, Hake A, Izadmehr S, Wiklund P, Oh WK, Szabo PM, Wind-Rotolo M, Unsal-Kacmaz K, Yao X, Schadt E, Sharma P, Bhardwaj N, Zhu J, Galsky MD. Wang L, et al. Among authors: farkas am. Clin Cancer Res. 2021 Aug 1;27(15):4287-4300. doi: 10.1158/1078-0432.CCR-20-4574. Epub 2021 Apr 9. Clin Cancer Res. 2021. PMID: 33837006 Free PMC article.
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer.
Salomé B, Sfakianos JP, Ranti D, Daza J, Bieber C, Charap A, Hammer C, Banchereau R, Farkas AM, Ruan DF, Izadmehr S, Geanon D, Kelly G, de Real RM, Lee B, Beaumont KG, Shroff S, Wang YA, Wang YC, Thin TH, Garcia-Barros M, Hegewisch-Solloa E, Mace EM, Wang L, O'Donnell T, Chowell D, Fernandez-Rodriguez R, Skobe M, Taylor N, Kim-Schulze S, Sebra RP, Palmer D, Clancy-Thompson E, Hammond S, Kamphorst AO, Malmberg KJ, Marcenaro E, Romero P, Brody R, Viard M, Yuki Y, Martin M, Carrington M, Mehrazin R, Wiklund P, Mellman I, Mariathasan S, Zhu J, Galsky MD, Bhardwaj N, Horowitz A. Salomé B, et al. Among authors: farkas am. Cancer Cell. 2022 Sep 12;40(9):1027-1043.e9. doi: 10.1016/j.ccell.2022.08.005. Cancer Cell. 2022. PMID: 36099881 Free PMC article.
Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling.
Farkas AM, Youssef D, Tran MA, Balan S, Newman JH, Audenet F, Anastos H, Velazquez LG, Peros A, Ananthanarayanan A, Daza J, Gonzalez-Gugel E, Sadanala K, Theorell J, Galsky MD, Horowitz A, Sfakianos JP, Bhardwaj N. Farkas AM, et al. bioRxiv [Preprint]. 2024 Sep 19:2024.04.30.591366. doi: 10.1101/2024.04.30.591366. bioRxiv. 2024. PMID: 38746459 Free PMC article. Preprint.
42 results