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The catechol moiety of obafluorin is essential for antibacterial activity.
Batey SFD, Davie MJ, Hems ES, Liston JD, Scott TA, Alt S, Francklyn CS, Wilkinson B. Batey SFD, et al. Among authors: alt s. RSC Chem Biol. 2023 Aug 21;4(11):926-941. doi: 10.1039/d3cb00127j. eCollection 2023 Nov 1. RSC Chem Biol. 2023. PMID: 37920400 Free PMC article.
Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A.
Edwards JL, Balthazar JT, Esposito DLA, Ayala JC, Schiefer A, Pfarr K, Hoerauf A, Alt S, Hesterkamp T, Grosse M, Stadler M, Golparian D, Unemo M, Read TD, Shafer WM. Edwards JL, et al. Among authors: alt s. mSphere. 2022 Oct 26;7(5):e0036222. doi: 10.1128/msphere.00362-22. Epub 2022 Sep 12. mSphere. 2022. PMID: 36094073 Free PMC article.
In Vitro-In Vivo Relationship in Mini-Scale-Enabling Formulations of Corallopyronin A.
Becker T, Krome AK, Vahdati S, Schiefer A, Pfarr K, Ehrens A, Aden T, Grosse M, Jansen R, Alt S, Hesterkamp T, Stadler M, Hübner MP, Kehraus S, König GM, Hoerauf A, Wagner KG. Becker T, et al. Among authors: alt s. Pharmaceutics. 2022 Aug 9;14(8):1657. doi: 10.3390/pharmaceutics14081657. Pharmaceutics. 2022. PMID: 36015283 Free PMC article.
INCATE: a partnership to boost the antibiotic pipeline.
Alt S, Haggstrom D, Kessmann H, Kloss F, Schneider CE, Jäger T, Schwede T, Brakhage A, Dehio C. Alt S, et al. Nat Rev Drug Discov. 2022 Sep;21(9):621-622. doi: 10.1038/d41573-022-00138-7. Nat Rev Drug Discov. 2022. PMID: 35974146 No abstract available.
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: alt s. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: alt s. Nat Rev Chem. 2021;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 34426795 Free PMC article. Review.
Long-lived tumor-associated macrophages in glioma.
Georgieva PB, Mathivet T, Alt S, Giese W, Riva M, Balcer M, Gerhardt H. Georgieva PB, et al. Among authors: alt s. Neurooncol Adv. 2020 Sep 25;2(1):vdaa127. doi: 10.1093/noajnl/vdaa127. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33205045 Free PMC article.
84 results