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Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma.
Woeste MR, Shrestha R, Geller AE, Li S, Montoya-Durango D, Ding C, Hu X, Li H, Puckett A, Mitchell RA, Hayat T, Tan M, Li Y, McMasters KM, Martin RCG, Yan J. Woeste MR, et al. Among authors: shrestha r. J Immunother Cancer. 2023 Apr;11(4):e006221. doi: 10.1136/jitc-2022-006221. J Immunother Cancer. 2023. PMID: 37072351 Free PMC article.
The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression.
Geller AE, Shrestha R, Woeste MR, Guo H, Hu X, Ding C, Andreeva K, Chariker JH, Zhou M, Tieri D, Watson CT, Mitchell RA, Zhang HG, Li Y, Martin Ii RCG, Rouchka EC, Yan J. Geller AE, et al. Among authors: shrestha r. Nat Commun. 2022 Feb 9;13(1):759. doi: 10.1038/s41467-022-28407-4. Nat Commun. 2022. PMID: 35140221 Free PMC article.
Differential Functional Responses of Neutrophil Subsets in Severe COVID-19 Patients.
McLeish KR, Shrestha R, Vashishta A, Rane MJ, Barati MT, Brier ME, Lau MG, Hu X, Chen O, Wessel CR, Spalding T, Bush SE, Ijemere K, Hopkins CD, Cooke EA, Tandon S, Manning T, Uriarte SM, Huang J, Yan J. McLeish KR, et al. Among authors: shrestha r. Front Immunol. 2022 May 31;13:879686. doi: 10.3389/fimmu.2022.879686. eCollection 2022. Front Immunol. 2022. PMID: 35711435 Free PMC article.
Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis.
Ding C, Shrestha R, Zhu X, Geller AE, Wu S, Woeste MR, Li W, Wang H, Yuan F, Xu R, Chariker JH, Hu X, Li H, Tieri D, Zhang HG, Rouchka EC, Mitchell R, Siskind LJ, Zhang X, Xu XG, McMasters KM, Yu Y, Yan J. Ding C, et al. Among authors: shrestha r. Nat Immunol. 2023 Feb;24(2):239-254. doi: 10.1038/s41590-022-01388-8. Epub 2023 Jan 5. Nat Immunol. 2023. PMID: 36604547 Free PMC article.
CXCL12 ameliorates neutrophilia and disease severity in SARS-CoV-2 infection.
Zheng J, Dhakal H, Qing E, Shrestha R, Geller AE, Morrissey SM, Saxena D, Hu X, Li H, Li H, Wilhelmsen K, Wendt LH, Klumpp K, Hume PS, Janssen WJ, Brody R, Palmer KE, Uriarte SM, Ten Eyck PP, Meyerholz DK, Merchant ML, McLeish K, Gallagher T, Huang J, Yan J, Perlman S. Zheng J, et al. Among authors: shrestha r. J Clin Invest. 2025 Jan 7:e188222. doi: 10.1172/JCI188222. Online ahead of print. J Clin Invest. 2025. PMID: 39773555 Free article.
1,914 results