Hagemann TL - Search Results

1

STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease.

Hagemann TL, Coyne S, Levin A, Wang L, Feany MB, Messing A. Hagemann TL, et al. Cells. 2023 Mar 23;12(7):978. doi: 10.3390/cells12070978. Cells. 2023. PMID: 37048051 Free PMC article.

2

Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction.

Hagemann TL, Gaeta SA, Smith MA, Johnson DA, Johnson JA, Messing A. Hagemann TL, et al. Hum Mol Genet. 2005 Aug 15;14(16):2443-58. doi: 10.1093/hmg/ddi248. Epub 2005 Jul 13. Hum Mol Genet. 2005. PMID: 16014634

3

Alexander disease-associated glial fibrillary acidic protein mutations in mice induce Rosenthal fiber formation and a white matter stress response.

Hagemann TL, Connor JX, Messing A. Hagemann TL, et al. J Neurosci. 2006 Oct 25;26(43):11162-73. doi: 10.1523/JNEUROSCI.3260-06.2006. J Neurosci. 2006. PMID: 17065456 Free PMC article.

4

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. Tang G, et al. Hum Mol Genet. 2008 Jun 1;17(11):1540-55. doi: 10.1093/hmg/ddn042. Epub 2008 Feb 14. Hum Mol Genet. 2008. PMID: 18276609 Free PMC article.

5

Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease.

Hagemann TL, Boelens WC, Wawrousek EF, Messing A. Hagemann TL, et al. Hum Mol Genet. 2009 Apr 1;18(7):1190-9. doi: 10.1093/hmg/ddp013. Epub 2009 Jan 7. Hum Mol Genet. 2009. PMID: 19129171 Free PMC article.

6

Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein.

Cho W, Hagemann TL, Johnson DA, Johnson JA, Messing A. Cho W, et al. Among authors: hagemann tl. J Neurochem. 2009 Jul;110(1):343-51. doi: 10.1111/j.1471-4159.2009.06146.x. Epub 2009 May 5. J Neurochem. 2009. PMID: 19457099 Free PMC article.

7

Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes.

Tian R, Wu X, Hagemann TL, Sosunov AA, Messing A, McKhann GM, Goldman JE. Tian R, et al. Among authors: hagemann tl. J Neuropathol Exp Neurol. 2010 Apr;69(4):335-45. doi: 10.1097/NEN.0b013e3181d3cb52. J Neuropathol Exp Neurol. 2010. PMID: 20448479 Free PMC article.

8

Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury.

Cengiz P, Kleman N, Uluc K, Kendigelen P, Hagemann T, Akture E, Messing A, Ferrazzano P, Sun D. Cengiz P, et al. Antioxid Redox Signal. 2011 May 15;14(10):1803-13. doi: 10.1089/ars.2010.3468. Epub 2010 Dec 4. Antioxid Redox Signal. 2011. PMID: 20712402 Free PMC article.

9

Strategies for treatment in Alexander disease.

Messing A, LaPash Daniels CM, Hagemann TL. Messing A, et al. Among authors: hagemann tl. Neurotherapeutics. 2010 Oct;7(4):507-15. doi: 10.1016/j.nurt.2010.05.013. Neurotherapeutics. 2010. PMID: 20880512 Free PMC article. Review.

10

Knockdown of MLC1 in primary astrocytes causes cell vacuolation: a MLC disease cell model.

Duarri A, Lopez de Heredia M, Capdevila-Nortes X, Ridder MC, Montolio M, López-Hernández T, Boor I, Lien CF, Hagemann T, Messing A, Gorecki DC, Scheper GC, Martínez A, Nunes V, van der Knaap MS, Estévez R. Duarri A, et al. Neurobiol Dis. 2011 Jul;43(1):228-38. doi: 10.1016/j.nbd.2011.03.015. Epub 2011 Apr 3. Neurobiol Dis. 2011. PMID: 21440627 Free PMC article.

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