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Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97.
Thejer BM, Infantino V, Santarsiero A, Pappalardo I, Abatematteo FS, Teakel S, Van Oosterum A, Mach RH, Denora N, Lee BC, Resta N, Bagnulo R, Niso M, Contino M, Montsch B, Heffeter P, Abate C, Cahill MA. Thejer BM, et al. Among authors: cahill ma. Int J Mol Sci. 2023 Mar 28;24(7):6381. doi: 10.3390/ijms24076381. Int J Mol Sci. 2023. PMID: 37047353 Free PMC article.
PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth.
Thejer BM, Adhikary PP, Kaur A, Teakel SL, Van Oosterum A, Seth I, Pajic M, Hannan KM, Pavy M, Poh P, Jazayeri JA, Zaw T, Pascovici D, Ludescher M, Pawlak M, Cassano JC, Turnbull L, Jazayeri M, James AC, Coorey CP, Roberts TL, Kinder SJ, Hannan RD, Patrick E, Molloy MP, New EJ, Fehm TN, Neubauer H, Goldys EM, Weston LA, Cahill MA. Thejer BM, et al. Among authors: cahill ma. BMC Mol Cell Biol. 2020 Apr 3;21(1):24. doi: 10.1186/s12860-020-00256-3. BMC Mol Cell Biol. 2020. PMID: 32245408 Free PMC article.
PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease.
Thejer BM, Adhikary PP, Teakel SL, Fang J, Weston PA, Gurusinghe S, Anwer AG, Gosnell M, Jazayeri JA, Ludescher M, Gray LA, Pawlak M, Wallace RH, Pant SD, Wong M, Fischer T, New EJ, Fehm TN, Neubauer H, Goldys EM, Quinn JC, Weston LA, Cahill MA. Thejer BM, et al. Among authors: cahill ma. BMC Mol Cell Biol. 2020 Apr 15;21(1):26. doi: 10.1186/s12860-020-00268-z. BMC Mol Cell Biol. 2020. PMID: 32293262 Free PMC article.
Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity.
Izzo NJ, Xu J, Zeng C, Kirk MJ, Mozzoni K, Silky C, Rehak C, Yurko R, Look G, Rishton G, Safferstein H, Cruchaga C, Goate A, Cahill MA, Arancio O, Mach RH, Craven R, Head E, LeVine H 3rd, Spires-Jones TL, Catalano SM. Izzo NJ, et al. Among authors: cahill ma. PLoS One. 2014 Nov 12;9(11):e111899. doi: 10.1371/journal.pone.0111899. eCollection 2014. PLoS One. 2014. PMID: 25390692 Free PMC article.
PGRMC1 Promotes Progestin-Dependent Proliferation of Breast Cancer Cells by Binding Prohibitins Resulting in Activation of ERα Signaling.
Bai Y, Ludescher M, Poschmann G, Stühler K, Wyrich M, Oles J, Franken A, Rivandi M, Abramova A, Reinhardt F, Ruckhäberle E, Niederacher D, Fehm T, Cahill MA, Stamm N, Neubauer H. Bai Y, et al. Among authors: cahill ma. Cancers (Basel). 2021 Nov 11;13(22):5635. doi: 10.3390/cancers13225635. Cancers (Basel). 2021. PMID: 34830790 Free PMC article.
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